这些发现提供了更多证据，表明了在可食用动物身上使用氟喹诺酮类药物会带来哪些问题。
The findings add to the growing body of evidence suggestive of the problems of using fluoroquinolonones in food-producing animals.
目的是探讨外排泵在嗜麦芽窄食单胞菌中对氟喹诺酮类药物的耐药性中的作用。
The objective is to explore the role of efflux pump in drug resistance to fluoroquinolones in Stenotrophomonas maltophilia.
对喹诺酮类药物过敏的患者忌用。
This drug is not for patients who have shown hypersensitivity to quinolones.
结论应高度重视氟喹诺酮类药物的不良反应。
CONCLUSION Attach the highly importance to ADRs of the fluoroquinolones.
结论老年人及特殊人群应慎重选择使用喹诺酮类药物；
Conclusion The elderly and special populations should be carefully chosen to use quinolones;
使用抗生素，特别是使用氟喹诺酮类药物，是一个危险因素。
Antibiotic use, especially use of fluoroquinolones, is a risk factor.
药敏试验结果表明，重组菌株失去对喹诺酮类药物的抗药性。
Do antibiotics sensitivity test on its recombinant strains, but no resistance of Quinolone can be found.
目的探讨大肠埃希菌靶位基因突变对喹诺酮类药物耐药的影响。
Objective To investigate the effects of target gene mutations on the quinolones resistance in Escherichia coli.
CCCP等能量抑制剂可加强细菌对氟喹诺酮类药物的摄取量。
The energy resistance inhibiter, such as CCCP, can intensify bacterial ingestion to fluoroquinolone drugs.
用离子抑制色谱进行水溶液中氧氟沙星等喹诺酮类药物含量的分析。
The contents of quinolone medicines such as ofloxacin etc in aqueous solution are analyzed by ion inhibition chromatography.
结果喹诺酮类药物在我院的使用逐年增加，成为抗菌药物中主要用药。
Results the amount of utilization of FQNLs increased year by year, FQNLs became the main medicine.
结果：归纳总结出氟喹诺酮类药物的不良反应发生的一般规律和有关特征。
RESULTS: The general rule and characteristics of occurrence of adverse reactions resulted from quinolones have been summarized.
目的：探讨主动外排泵在嗜麦芽寡养单胞菌对氟喹诺酮类药物耐药中的作用。
Objective:To explore the role of efflux pump in drug resistance to fluoroquinolones in Stenotrophomonas maltophilia.
注意：不要以为氟喹诺酮类药物对假单胞菌都有相同的功效，因为这不是事实；
NOTES: do not assume that all fluoroquinolones have equal efficacy against Pseudomonas, because they don't;
目的研究导致大肠埃希菌dna回旋酶a亚单位的基因变异耐喹诺酮类药物的机制。
OBJECTIVE to study the mutation in DNA gyrase a of Escherichia coli resistante to quinolone antibiotics.
喹诺酮类药物在临床中广泛应用于治疗各种感染，但是在其应用中也发现了许多不良反应。
Quinolones antibacterials have been used widely in the treatment of many kinds of infectious disease in clinic.
结果氟喹诺酮类药物具有不错的市场应用前景，但需注意可能的不良反应及耐药性的发生。
Results the results indicate that fluoroquinolone had perfect market prospect, however, the possible adverse drug reactions and resistance should be paid much attention.
但人型枝原体、解脲脲原体的喹诺酮类药物耐药株对YH16、YH17也存在交叉耐药性。
However, there were cross resistance YH16 and YH17 for Uu and Mh strains resistant to other quinolones.
结果皮质类固醇对肌腱的影响仍存在争议，应用喹诺酮类药物治疗可能和肌腱疾病的发生有关。
Results There still were many arguments about the effect of corticosteroid on the treatment of tendon disease.
目的：评价几种喹诺酮类药物对幼龄兔软骨细胞的相对毒性，软骨毒性与浓度、时间、年龄的关系。
AIM: To evaluate the relation between the relative toxicity, chondrotoxicity of some kinds of quinolones on chondrocytes of younger rabbits and the concentration, animal age, treatment duration.
第三代喹诺酮类药物，即氟喹诺酮类药物，具有抗菌谱广、抗菌作用强、作用迅速、副作用少等优点。
F-quinolones, as the third generation of quinolones, have many advantages such as broad antimicrobial spectrum, strong and fast antimicrobial effects and a few side-effects.
光谱分析结果表明，上述喹诺酮类药物都可以与牛乳铁蛋白或人血清白蛋白之间形成亲和力较强的复合物。
The spectroscopy analysis shows that all those quinolone drugs can react with BLf or HSA and form a drug-protein compound.
在736例喹诺酮类药物ADR中，以神经系统损害最多，其次是光毒性、消化系统损害、心血管系统损害等；
In 736 ADR cases reports of quinolone antibacterial agents, the nervous system was the most damage, followed by light toxicity, digestive system damage and cardiovascular system damage.
本文简要回顾了部分氟喹酮类药物的PK/PD研究，并对莫西沙星等主要氟喹诺酮类药物PK/PD参数进行总结。
In this article, we review PK/PD investigation of fluoroquinolones, and give a summary of PK/PD parameter of moxifloxacin and some other fluoroquinolones.
喹诺酮类药物(如氧氟沙星、诺氟沙星、环丙沙星等)抗生素以其高效、广谱、服用方便等优点在临床上发挥了越来越重要的作用。
Quinolones gets more and more use in the clinic for its advantages of high activity, broad spectrum and the convenience in the taking, et al.
目的：研究不同药物浓度、不同化学结构的氟喹诺酮类药物对突变选择窗(MSW)内筛选的大肠埃希菌耐药突变体的靶位耐药基因的影响。
OBJECTIVE To investigate the effect of drug concentration, drug structure of fluoroquinolones on the resistant gene of Escherichia coli mutants selected in the mutant selection window (MSW).
喹诺酮类、 大环内酯类、抗感染中成药类抗感染药物以及生物制品与生化药物、维生素类药物均有增长；
Anti-infectious agents like quinolones, macrolides, TCM with anti-infectious effect and biologicals & biochemicals, vitamins had grown.
药敏试验结果表明，喹诺酮类、头孢菌素类和氨基糖苷类药物的效果较好。
The drug susceptibility testing indicates that Quinotones, Cephazolins and Aminoglycosides have good inhibitory effection.
药敏试验结果表明，喹诺酮类、头孢菌素类和氨基糖苷类药物的效果较好。
The drug susceptibility testing indicates that Quinotones, Cephazolins and Aminoglycosides have good inhibitory effection.
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