方法：以包封率和平均粒径为评价指标，采用星点设计-效应面法优化醇质体处方中大豆磷脂、药物和无水乙醇的最佳配比。
METHODS Taking encapsulated ratio and average diameter as evaluation index to optimize the best matching of soybean phospholipid, drug and absolute alcohol in ethosomes.
结果：通过调节药物浓度和不同高分子组合筛选出突释小，包封率高且缓慢释放的处方。
Results: By adjusting LDME concentration and different polymer combinations, we achieved microspheres with high encapsulation efficiency, low initial burst and sustained release.
利用扫描电镜和紫外光谱考察了内相聚合物浓度和搅拌速度对微球粒径和药物包封率的影响。
The effects of polymer concentration and agitation rates on the size of microspheres and drug incorporation efficiency were studied by scanning electronic microscopy (SEM) and UV-spectrophotometry.
本发明制备工艺简单，所 得纳米粒子粒径均匀，粒度分布较窄，对疏水性药物有较高的载药量和包封率。
The invention has simple process, uniform grain diameter, narrow graininess distribution, high carrier and packing rate on hydrophobic drug.
考察了药物与磷脂的复合率，磷脂复合物脂质体的包封率，粒径大小和分布，以及体外释药特性。
The drug loading rate, encapsulation efficiency, particle distribution and in vitro release of Lac-NCTD from liposomes were investigated, respectively.
考察了药物与磷脂的复合率，磷脂复合物脂质体的包封率，粒径大小和分布，以及体外释药特性。
The drug loading rate, encapsulation efficiency, particle distribution and in vitro release of Lac-NCTD from liposomes were investigated, respectively.
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