虽然许多原癌基因和肿瘤抑制基因被广泛表达,这些基因的突变与特定的器官或细胞类型的癌有关。
Although many proto-oncogenes and tumor suppressor genes are widely expressed, the mutation of these genes is associated with cancer of specific organs or cell types.
近年来的研究发现,许多癌基因和抑癌基因相关产物为细胞生长、增殖、分化等信号转导途径的成员。
It is known that many related products of oncogenes and anti - oncogenes take part in the signal transduction of grow, proliferation and differentiation of cells.
其作用机理为抗氧化作用,抗细胞增殖,诱导细胞调亡,干预细胞转导和增强抑癌基因表达,干预细胞周期等。
The mechanism are antioxidation, cell proliferation suppression, apoptosis induction, cell signal transduction disturbing and tumor suppression gene activity enhancing, cell cycle disturbing etc.
肿瘤形成与控制细胞生长和分化的多种基因特别是癌基因、抑癌基因的遗传改变有关。
There are multiple genes especially oncogenes and tumor suppressor genes involved in 'the genetic alterations which regulating the growth and differentiation of cells.
人抑癌基因,其编码的蛋白,含有其的表达载体和由该载体转化的细胞。
Human cancer suppressor gene, protein encoded therein, expression vector containing the same, and cell transformed by the vector.
目前在分子水平上的研究显示肿瘤的发生与癌基因的激活和抑癌基因的失活以及细胞周期调节失控密切相关。
It has been proved that the occurrence of oncogenesis is in close relationship with the oncogene activation, the tumor suppressor gene inactivation and the disorder of cell cycle modulation.
癌基因,肿瘤抑制基因的发现促进了对细胞周期及细胞凋亡机制的深入理解。使人们对肿瘤发生和发展的认识也日趋深入。
The discovery of oncogene and tumor suppressor gene has deepened human beings understanding of the mechanisms of cell cycle and cell apoptosis as well as the mechanisms of tumorigenesis.
目的探讨外源野生型PTEN抑癌基因对人高转移性黏液表皮样癌细胞系m 3sp2体外黏附、迁移和侵袭特性的影响。
Objective To study effects of the exogenous wild-type PTEN tumor suppressor gene on in vitro adhesion, migration and invasion of the highly metastatic mucoepidermoid carcinoma cell line M3SP2.
综述了一些癌基因、肿瘤抑制基因和DNA修复基因对细胞电离辐射敏感性的影响。
Reported effects of some oncogenes, tumour suppressor genes and DNA repair genes on sensitivity of cells to ionizing radiation are reviewed.
EBV潜伏膜蛋白基因LMP1和核抗原基因EBNA2是公认的导致细胞恶性转化的病毒癌基因。
The EBV latent membrane protein (LMP1) gene and nucleoantigen gene EBNA2 are virus-oncogene, which can induce malignant transformation of cells.
癌基因和抑癌基因的发现,细胞信号传导通路的阐明,极大地丰富了人们对细胞癌变机制的认识。
The discovery of oncogenes and tumor suppressor genes, and the research of signal transduction pathway yield profound insights into the mechanisms of carcinogenesis.
目的:培养建立中国人种前列腺癌细胞系,为了解中国人种前列腺癌细胞生长特性、进一步开展前列腺癌基因诊断和药物筛选建立方便的实验手段和模型打下基础。
Objective: To culture and establish Chinese ethnic prostate cancer cell line, investigate its growth characterization and explore experimental methods and models of gene diagnosis and trial of drugs.
研究肺癌抑癌基因1 (TSLC1)对人前列腺癌t 3 B细胞侵袭、成瘤和转移能力的影响。
To investigate the effects of tumor suppressor in lung cancer-1 (TSLC1) on cell aggression, tumor formation and capability of metastasis in human prostatic carcinoma cell line T3B.
抑癌基因p53编码转录因子p53蛋白在调控癌基因表达、dna合成和损伤修复以及细胞凋亡中起关键作用。
The tumor suppressor gene p53 codes for a transcription factor, p53 protein, plays a critical regulation role in oncogene expression, DNA synthesis and repair systems, and cell apoptosis.
关于癌基因诱导细胞衰老和癌症发生的关系…
Oncogene-Induced Cell Senescence ― Halting on the Road to Ca…
中医药在抑制血管生成、促进细胞凋亡、调节内分泌系统和抑制癌基因表达方面对癌前病变的干预作用。
Traditional Chinese medicine (TCM) has shown effects on precancerous changes through inhibiting angiogenesis, promoting apoptosis, modulating endocrine system and restraining oncogene expression.
这太有趣了,肿瘤基因(抑癌基因和原癌基因)的表达与多细胞生物体在遗传发生层面的形态协同一致的。
It is of interest that the coordinated expression of "cancer genes" (tumor supressors and oncogenes) coincides with the appearance of multicellularity in the filogenetic scale.
结论外源性pten抑癌基因对高转移性黏液表皮样癌细胞系m 3sp2体外黏附、迁移和侵袭具有抑制作用。
Conclusion the exogenous wild-type PTEN gene has significant effects of anti-adhesion, anti-migration, and anti-invasion on the highly metastatic mucoepidermoid carcinoma cell line M3SP2.
结论外源性pten抑癌基因对高转移性黏液表皮样癌细胞系m 3sp2体外黏附、迁移和侵袭具有抑制作用。
Conclusion the exogenous wild-type PTEN gene has significant effects of anti-adhesion, anti-migration, and anti-invasion on the highly metastatic mucoepidermoid carcinoma cell line M3SP2.
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