目的：研究苦参碱和氧化苦参碱降转氨酶活性，以期评价二者的肝保护作用。
Objective: to study effects of matrine and oxymatrine on level of serum aminotransferases for evaluating their activities to protect against hepatic damage.
目的：建立用HPLC同时测定苦参药材中苦参碱和氧化苦参碱的含量测定方法。
Objective: to establish a high performance liquid chromatography (HPLC) method to determine the contents of matrine and oxymatrine in Sophora flavescens Ait.
结论在苦参的提取过程中，苦参碱和氧化苦参碱的转化对苦参提取工艺造成了影响。
Conclusion in the process of extracting, it had effect to transformation between matrine a...
目的从山豆根中精制苦参碱和氧化苦参碱，并以此为化学对照品对山豆根药材进行薄层色谱鉴别。
OBJECTIVE to isolate and purify the two alkaloids matrine and oxymatrine and then to identify the commercial medicinal material of "Shandougen" by TLC.
其主要活性物质是生物碱类和黄酮类，对其中的苦参碱和氧化苦参碱的药代动力学有初步的研究。
The compounds of Alkaloidss and flavonoids are main active composition, and there is a preliminary study on the pharmacokinetics of matrine alkaloids and oxymatrine.
苦参碱和氧化苦参碱高、中、低3种浓度的平均回收率分别为106 96 %和105 04 % ，日内、日间精密度分别小于13 %和7 %。
The average recoveries of matrine and oxymatrine were 106.96% and 105.04%, respectively. RSDs of within-day and between-day were lower than 13% and 7% respectively.
方法采用大鼠在体肠灌流吸收实验，研究了氧化苦参碱的吸收部位和吸收动力学特征。
METHODS: The absorption kinetics and absorption site of oxymatrine were investigated using in situ perfusion method in rats.
结论氧化苦参碱在体外具有抑制大鼠贮脂细胞增殖和胶原合成的作用，这对防治肝纤维化可能有一定的临床应用价值。
Conclusion Oxymatrine has the inhibiting potential of rat hepatic stellate cells in vitro, which might be of practical clinical value in prevention and treatment of hepatic fibrosis.
目的观察氧化苦参碱(O MT)对癫痫大鼠脑组织丙二醛(MDA)浓度和超氧化物歧化酶(SOD)活性的影响。
Objective To study the effect of Oxymartrine (OMT) on the concentration of malondialdehyde (MDA) and the enzyme activity of superoxide dismutase (SOD) in the brain tissue of epileptic rats.
通过对溶剂、提取次数、碱化条件的选择，用离子交换和重结晶的方法提取纯化氧化苦参碱。
Through selecting extracting solvent, extracting times and alkalinizing method, Oxymatrine is extracted and purified by ion-exchanging and re-crystallization.
目的考察氧化苦参碱负电荷脂质体的处方和制备工艺，并研究其理化性质。
OBJECTIVE To investigate the formulation and preparation technique of anionic oxymatrine liposomes, and determine its physicochemical properties.
采用正交试验法，以干浸膏得率和苦参碱、氧化苦参碱转移率为评价指标，优选水提取药材的提取工艺和精制工艺；
The dried extraction yield and transfer rate of matrine and oxymatrine were adopted as markers in the orthogonality test to optimize the water extraction and purification procedure of herbs;
采用正交试验法，以干浸膏得率和苦参碱、氧化苦参碱转移率为评价指标，优选水提取药材的提取工艺和精制工艺；
The dried extraction yield and transfer rate of matrine and oxymatrine were adopted as markers in the orthogonality test to optimize the water extraction and purification procedure of herbs;
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