有巨大的癌基因和抑癌基因的癌症有关。
There are enormous oncogenes and suppressor genes involved in cancer.
目的:从基因水平了解正常胃和胃癌组织原癌基因和抑癌基因表达的分子机制。
Objective: To study the expressions of pro-onc and tumor suppressor genes in gastric cancer by cDNA expression array.
而某些癌基因和抑癌基因对HIF-1表达及活性的影响最终决定着肿瘤的预后。
The influencing of some oncogene and anti-oncogene to the expression and activity of HIF-1 determines neoplastic prognosis ultimately.
目的探讨胃癌组织中甲基化酶、去甲基化酶基因与肿瘤相关癌基因和抑癌基因的关系。
Objective To investigate the relationship of the expression of DNA methyltransferase, demethylase(mbd2) and tumor-associated genes in human gastric cancer.
目的:探讨癌基因P2 1和抑癌基因P16的表达与膀胱癌生物学行为之间的关系。
Purpose:Find the relationship between the expressions of P21 oncogene, P16 antioncogene and the biological action of the bladder cancer.
近来对新发现的肿瘤转移抑制基因NM 23和抑癌基因pten引起了人们极大关注。
Recently, the new discovered NM23 gene (a tumor metastasis suppressor gene) and PTEN gene (a tumor suppressor gene) cause people's attention extensively.
癌基因和抑癌基因的发现,细胞信号传导通路的阐明,极大地丰富了人们对细胞癌变机制的认识。
The discovery of oncogenes and tumor suppressor genes, and the research of signal transduction pathway yield profound insights into the mechanisms of carcinogenesis.
近年来的研究发现,许多癌基因和抑癌基因相关产物为细胞生长、增殖、分化等信号转导途径的成员。
It is known that many related products of oncogenes and anti - oncogenes take part in the signal transduction of grow, proliferation and differentiation of cells.
目前在分子水平上的研究显示肿瘤的发生与癌基因的激活和抑癌基因的失活以及细胞周期调节失控密切相关。
It has been proved that the occurrence of oncogenesis is in close relationship with the oncogene activation, the tumor suppressor gene inactivation and the disorder of cell cycle modulation.
鉴定和研究相关癌基因和抑癌基因的功能有望为肺癌防治提供新的靶标,因而一直是肺癌研究领域内的热点。
Identification and research on the oncogenes and the tumor suppressor genes will provide new targets of prevention and treatment to lung cancer.
因此,探讨不同类型肿瘤相关癌基因和抑癌基因是认识肿瘤发生分子机理、开展基因诊断和基因治疗的基本前提。
Therefore, the detection of oncogenes and TSGs in different tumors is the basic prerequisite to understand the mechanism of tumorigenesis and to conduct gene diagnosis and gene therapy.
目的探讨癌基因MMP - 9和抑癌基因RECK在喉癌组织中的表达与喉癌临床特征的关系,了解喉癌的生物学行为,并研究两种基因的表达相关性。
ObjectiveTo investigate the relation between expression of MMP-9 and RECK in laryngeal carcinoma and it's clinical characteristics and to explore the biological action of laryngeal tumor.
其作用机理为抗氧化作用,抗细胞增殖,诱导细胞调亡,干预细胞转导和增强抑癌基因表达,干预细胞周期等。
The mechanism are antioxidation, cell proliferation suppression, apoptosis induction, cell signal transduction disturbing and tumor suppression gene activity enhancing, cell cycle disturbing etc.
肿瘤形成与控制细胞生长和分化的多种基因特别是癌基因、抑癌基因的遗传改变有关。
There are multiple genes especially oncogenes and tumor suppressor genes involved in 'the genetic alterations which regulating the growth and differentiation of cells.
目的探讨抑癌基因DPC4和PTEN蛋白在大肠癌的表达及临床意义。
Objective To explore the expression and clinical significance of PTEN and DPC4 gene in large intestine carcinoma.
虽然有事实证明一些微小rna能够起癌基因或者抑癌基因,但是其在肿瘤的侵袭和转移中的作用尚未有研究。
Although there is emerging evidence that some microRNAs can function as oncogenes or tumour suppressors, the role of microRNAs in mediating cancer metastasis remains unexplored.
人抑癌基因,其编码的蛋白,含有其的表达载体和由该载体转化的细胞。
Human cancer suppressor gene, protein encoded therein, expression vector containing the same, and cell transformed by the vector.
D5S471和D5S592附近可能存在食管癌的候选抑癌基因。
There probably existed candidate tumor suppressor gene (s) around D5S592 and D5S471.
目的探讨外源野生型PTEN抑癌基因对人高转移性黏液表皮样癌细胞系m 3sp2体外黏附、迁移和侵袭特性的影响。
Objective To study effects of the exogenous wild-type PTEN tumor suppressor gene on in vitro adhesion, migration and invasion of the highly metastatic mucoepidermoid carcinoma cell line M3SP2.
目的:探讨卵巢癌病变中P16抑癌基因的改变和可能的作用机制。
Objective: To explore the alteration and the possible mechanism of tumor suppressor gene P16 in the progression of ovarian carcinoma.
研究肺癌抑癌基因1 (TSLC1)对人前列腺癌t 3 B细胞侵袭、成瘤和转移能力的影响。
To investigate the effects of tumor suppressor in lung cancer-1 (TSLC1) on cell aggression, tumor formation and capability of metastasis in human prostatic carcinoma cell line T3B.
抑癌基因p53编码转录因子p53蛋白在调控癌基因表达、dna合成和损伤修复以及细胞凋亡中起关键作用。
The tumor suppressor gene p53 codes for a transcription factor, p53 protein, plays a critical regulation role in oncogene expression, DNA synthesis and repair systems, and cell apoptosis.
而肿瘤的发生与抑癌基因和癌基因密切相关。
And the occurrence of tumor is closely related to oncogenes and anti-oncogenes.
这太有趣了,肿瘤基因(抑癌基因和原癌基因)的表达与多细胞生物体在遗传发生层面的形态协同一致的。
It is of interest that the coordinated expression of "cancer genes" (tumor supressors and oncogenes) coincides with the appearance of multicellularity in the filogenetic scale.
结论外源性pten抑癌基因对高转移性黏液表皮样癌细胞系m 3sp2体外黏附、迁移和侵袭具有抑制作用。
Conclusion the exogenous wild-type PTEN gene has significant effects of anti-adhesion, anti-migration, and anti-invasion on the highly metastatic mucoepidermoid carcinoma cell line M3SP2.
这种平衡有赖于癌基因、抑癌基因和某些调节肽的…
The balance is regulated by pro-oncogene, suppressor oncogene and some regulatory peptide.
这种平衡有赖于癌基因、抑癌基因和某些调节肽的…
The balance is regulated by pro-oncogene, suppressor oncogene and some regulatory peptide.
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