《国际糖尿病》:罗格列酮和吡格列酮对心血管的影响是否有所差别?二者有何相似性?
International Diabetes: Do rosiglitazone and pioglitazone have different or similar properties in respect to their cardiovascular profiles?
《国际糖尿病》:二甲双胍通常被看作是胰岛素增敏剂。在改善胰岛素抵抗方面,二甲双胍和吡格列酮的区别有哪些?
International Diabetes: metformin is often viewed as an insulin sensitizer. What is the difference between metformin and pioglitazone with regard to improving insulin resistance?
二甲双胍和吡格列酮都是胰岛素增敏剂,因此这两类药物不会导致低血糖,而GLP-1类似物或DPP-IV抑制剂导致低血糖的概率也很低。
The metformin and pioglitazone are insulin sensitizers so they never lower you blood glucose below normal and the GLP-1 analogues or DPP-IV inhibitors also never lower your blood glucose below normal.
目的观察吡格列酮对2型糖尿病患者胰岛素敏感性和脂代谢的影响。
Objective Observe the effect of pioglitazone on insulin sensitivity and lipid metabolism in type 2 Diabetes Mellitus Patients.
目的:调查2型糖尿病患者加用吡格列酮所致水肿的临床特点及肝肾功能和促甲状腺激素水平的变化。
Objective: To investigate the clinical features of oedema and the changes in liver and renal function and thyrotropin level in type 2 diabetic patients following the addition of pioglitazone.
目的观察胰岛素或胰岛素加吡格列酮治疗磺脲类继发失效2型糖尿病的疗效和安全性。
Objective It is to observe the curative effect and safety of insulin or insulin combined with pioglitazone on type 2 diabetes with sulfonylurea secondum refractoriness.
使用罗格列酮或吡格列酮治疗的老年医保患者发生急性心肌梗塞,卒中,心力衰竭和死亡的危险性。
Risk of Acute Myocardial Infarction, Stroke, Heart Failure, and Death in Elderly Medicare Patients Treated With Rosiglitazone or Pioglitazone.
结论:在不同的糖尿病人中,吡格列酮明显降低死亡,心肌梗塞,和中风。
CONCLUSIONS: Pioglitazone is associated with a significantly lower risk of death, myocardial infarction, or stroke among a diverse population of patients with diabetes.
吡格列酮与糖尿病患者膀胱癌和其他常见癌症的风险。
Pioglitazone Use and Risk of Bladder Cancer and Other Common Cancers in Persons With Diabetes.
目的观察吡格列酮和阿托伐他汀联合应用对冠心病合并2型糖尿病PCI术后患者抗炎症作用的影响。
Objective To observe the antiinflammatory effect of pioglitazone combined with atorvastatin in the patients with coronary heart disease complicated with type-2 diabetes after PCI.
吡格列酮还能显著减轻PAN诱导的足细胞凋亡和坏死,而恢复足细胞的分化功能。
Further, pioglitazone significantly decreased PAN-induced podocyte apoptosis and necrosis while restoring podocyte differentiation.
调整后的其它因素,考虑个人罗格列酮有百分之十五较高的死亡和百分之十三的风险更大心脏衰竭而那些吡格列酮。
After adjusting for other factors, individuals taking rosiglitazone had a 15 percent higher rate of death and a 13 percent greater risk of heart failure compared with those taking pioglitazone.
吡格列酮与糖尿病患者膀胱癌和其他常见癌症的风险。
OBJECTIVE: To examine whether pioglitazone use for diabetes is associated with risk of bladder and 10 additional cancers.
吡格列酮与糖尿病患者膀胱癌和其他常见癌症的风险。
OBJECTIVE: To examine whether pioglitazone use for diabetes is associated with risk of bladder and 10 additional cancers.
应用推荐