目的探讨吴茱萸碱抗肿瘤的作用机制。
Objective To explore the mechanism of evodiamine in treating Carcinoma.
目的：研究吴茱萸提取物是否具有体外抗菌作用。
Objective:To study the antibacterial activity of extracts of Evodia rutaecarpa(Juss. )Benth in vitro.
目的：研究吴茱萸次碱对离体大鼠室颤阈的影响。
Objective: To investigate the effect of rutaecarpine on the ventricular fibrillation threshold (VFT) of isolated rat heart.
对近年来有关吴茱萸有效成分的药理研究进行概括。
The effective components in Fructus Evodiae have lots of pharmacological effects.
乙醇对吴茱萸碱洗脱能力较强而对吴茱萸次碱则较弱；
Evodiamine can be desorped by 90% alcohol, but Rutaecarpin almost can't.
目的研究吴茱萸碱体外诱导l 929细胞死亡的机制。
Objective To study the mechanism of L929 cell death induced by Evodiamine in vitro.
目的：建立涵水胶囊中吴茱萸次碱的高效液相色谱测定方法。
Objective:To develop an HPLC method for determining rutecarpine in Hanshui capsules.
目的考察黄连与吴茱萸分煎后二药配伍时主要组分的含量变化规律。
OBJECTIVE To investigate the contents variation of main chemical constituents during combination of Rhizoma Coptidis with Fructus Evodiae after separated decoction.
方法：以乙酸乙酯为溶剂用超声震荡提取法提取吴茱萸碱和吴茱萸次碱。
METHODS: Evodiamine and rutaecarpine were extracted with the solvent ethyl acetate and the ultrasonic extractor.
本法具有科学、先进、可行的特点，可望成为评价吴茱萸质量的常规方法。
The problem of the species identification and quality grading assessment can be carried out with this method.
结果：吴茱萸不同炮制品绿原酸的含量较吴茱萸生品均有不同程度的降低。
Result: the contents of chlorogenic acid in Evodia and processed products was different, which in the processed products were lower than Evodia.
鱼药丑牛10号是用油樟、岩桂、紫穗槐、吴茱萸、安息香等植物配成的制剂。
Chouniu No. 10 is a fishery medicine made from Cinnamomum Ionge-paiculatum, Cinnamomum petrophilium, Amorpha fruticosa, Evodia rut-aecarpa, Styrax hypoglauca.
各峰在峰强度上有差异，体现了不同产地吴茱萸所含化学成分在含量上有差别；
The intensity of each peak was different, reflecting that the content of chemical ingredients contained in E. rutaecarpa from different places were different.
结果表明吴茱萸汤对多种方法所致的急、慢性溃疡模型均有明显的治疗及预防作用。
The results indicate that WZYD has the obvious treatment and prevention effects on acute and chronic PU model making by all kinds of ways.
目的研究吴茱萸次碱(WZY)在人肝微粒体中对细胞色素P 450酶的抑制作用。
OBJECTIVE to determine the inhibitory effect of rutaecarpine (WZY) on cytochrome P450s in human liver microsome.
结果实验表明，煎煮次数、溶媒用量对吴茱萸次碱的提取影响较大，煎煮时间则次之。
Result The experiment show that decoction time and menstruum dosage have the evidence influence on extracting rutaecarpine, and decoction hour take second place.
结论：吴茱萸碱可明显抑制胃癌细胞侵袭力，其机制可能与下调PLK1基因表达有关。
Conclusion: Evodiamine could inhibit invasion of human gastric carcinoma cell through down regulating of PLK1 expression.
目的用核磁共振氢谱(1h - NMR)指纹图谱对吴茱萸和其伪品花椒、蚕砂进行鉴别。
Objective 1h-nmr fingerprints was established to identify Evodiae, Pericarpium Zanthoxylum and Feculae Bombycis.
结果：吴茱萸提取物对10种临床常见细菌有不同程度的抑制作用而对三种真菌无明显作用。
Results:Extracts of Evodia rutaecarpa(Juss. )Benth showed to exert different antibacterial effects on the 10 bacteria strains while no effect to 3 fungus strains.
目的观察吴茱萸次碱对大鼠心肌缺血再灌注损伤的保护作用是否与激活辣椒素敏感的感觉神经有关。
OBJECTIVE To determine whether the protection of rutaecarpine against myocardial ischemia-reperfu-sion injury is related to the activation of capsaicin-sensitive sensory nerves in rats.
结果：贵州余庆产12批吴茱萸药材的薄层色谱图和轮廓图十分相似，均有6个斑点和对应的6个峰；
Result: The TLC chromatogram and the contour chromatogram of 12 groups of crude drugs from Guizhou Yuqing were very similar, which had 6 spots and 6 corresponding peaks.
结果黄连、吴茱萸各配比组均能不同程度的抑制大鼠胃酸分泌及溃疡指数，其中以6：1实验组作用最强。
RESULTS All the compatibility of Coptis chinensis Franch and Evodia rutaecarpa(Juss) Benth showed some action and the best compatibility is 6:1.
结论：所建立的HPLC指纹图谱能体现吴茱萸的主要成分，可结合含量测定用于全面控制吴茱萸的质量。
Conclusion: the HPLC fingerprint established could reflect the main constituents of Euodiae Fructus, and could combine with content determination to take an overall control of Euodiae Fructus.
目的：研究吴茱萸超微饮片的HPLC指纹图谱，考察其有效成分含量，为吴茱萸超微饮片的质控提供可靠方法。
Objective: to determine the HPLC fingerprint of the Ultramicro Fructus Evodiae and to test its potent constituent content.
结果：确定吴茱萸汤的药效物质基础主要为产生X4，X9，X10和X12号色谱峰中的化学成分（已确认X9为吴茱萸次碱）。
RESULTS: The material basis of the Wuzhuyu decoction was found to be produced chiefly by the chemical constituents contained in No. X4, X9 (rutaecarpine), X10 and X12 chromatographic peaks.
目的：对比吴茱萸碱与化疗药物对A375 - S2细胞的细胞毒活性，并且研究PKC及ERK激酶在吴茱萸碱诱导a 375 -S2细胞死亡中的作用。
AIM: to compare the cytotoxic effect of evodiamine with chemotherapy drugs on A375-S2 cells, and to examine the relationship between the effects of PKC and ERK on evodiamine-induced cell death.
目的：对比吴茱萸碱与化疗药物对A375 - S2细胞的细胞毒活性，并且研究PKC及ERK激酶在吴茱萸碱诱导a 375 -S2细胞死亡中的作用。
AIM: to compare the cytotoxic effect of evodiamine with chemotherapy drugs on A375-S2 cells, and to examine the relationship between the effects of PKC and ERK on evodiamine-induced cell death.
应用推荐