吡喹酮是否具有免疫调节作用?
发现绦虫和吸虫感染者用吡喹酮驱治。
For cases of mixed infection of cestode or trematode praziquantel was used.
目前首选治疗药物为吡喹酮;
吡喹酮可以作为肝星状细胞激活的抑制剂。
The praziquantel can be used as an inhibitor for the activation of the hepatic stellate cells.
结果高浓度吡喹酮溶液具有很好的稳定性。
RESULTS The praziquantel solution at high concentration showed good stability.
吡喹酮是唯一可用于治疗各种类型血吸虫病的药物。
Praziquantel is the only available treatment against all forms of schistosomiasis.
高效液相色谱法测定透皮到家兔血液中吡喹酮的浓度。
The praziquantel concentrations in rabbit plasma were determined by HPLC.
目的:制备吡喹酮水凝胶栓剂,并建立其含量测定方法。
OBJECTIVE: to prepare praziquantel aquogel suppositories and to establish its assay method.
本文对可能影响到吡喹酮杀虫作用的宿主因素进行综述。
In this paper some host factors involved in the killing process of schistosomes induced by praziquantel were summarized.
公共卫生专家担心,蠕虫将会对这种叫做吡喹酮的药物产生一种抗体。
Public health experts worry that the worms will become resistant to this drug, praziquantel.
吡喹酮是广谱抗寄生虫药物,对各类血吸虫均有杀灭作用。
Praziquantel is a broad spectrum antiparasitic drug and has remarkable activity against all species of schistosomas.
本发明提供了吡喹酮在制备肝星状细胞激活抑制剂中的应用。
The invention provides an application of praziquantel in preparing a hepatic stellate cell activator-inhibitor.
结论高浓度吡喹酮溶液有望成为吡喹酮的新型透皮给药制剂。
CONCLUSION the solution containing high praziquantel concentration may be a promising vehicle for the transdermal delivery of praziquantel.
芬苯达唑组虫卵发育成含胚卵。吡喹酮组之虫卵发育成含卷曲钩蚴。
In case of groups treated with flubendazole, fenbendazole or praziquantel, eggs showed cell division, or developed into ovum containing embryo or ovum containing a curling tapeworm.
本发明提供了吡喹酮在制备抗日本血吸虫病肝脏纤维化药物中的应用。
The invention provides an application of praziquantel in preparing medicines for resisting Japanese schistosomiasis liver fibrosis.
作者建立了高效正相色谱法,测定脑囊虫病人脑脊液和血浆吡喹酮浓度。
A normal phase high performance liquid chromatographic (HPLC) method was developed for the determination of praziquantel in plasma and cerebral spinal fluid (CSF) of cerebral cysticercosis patients.
本文综述了近30年来国、内外实验室对吡喹酮抗血吸虫作用的研究进展。
This paper summarizes the 30 years' research progress on the mode of action of the drug against schistosomes proceeded by domestic and abroad laboratories.
目的:直接比较吡喹酮和阿苯达唑治疗大鼠异盘肺吸虫病的效果和毒性反应。
Purpose:Directly compare the effects with side effects of praziquantel and albendazole on the Paragonimiasis heterotremus in rats.
世卫组织血吸虫病控制战略的重点是,通过使用吡喹酮进行定期、有针对性的治疗,遏制该疾病。
The WHO strategy for schistosomiasis control focuses on reducing disease through periodic, targeted treatment with praziquantel.
于1980年9月以一次口服吡喹酮粉观察治疗羊人工感染的程氏东毕吸虫病的效果。
In September, 1980. 12 sheep were artificially infected with Orientobilharzia Cheni, and were divided into 4 groups in each group.
对吡喹酮杀灭肺吸虫的可能机制及治疗幼虫寄生型肺吸虫病的合适剂量与疗程作了探讨。
Finally, the possible mechanism of killing Paragonimus of praziquantel and the optimal dose and course of treatment were discussed.
以吡喹酮反复群体化疗,辅以灭螺的综合防治手段,在血吸虫病的防治上产生了显著的效果。
The comprehensive control measure based on the chemotherapy of praziquantel, combined with snail control in epidemic areas has made great achievements for the control of schistosomiasis.
其治疗效果比吡喹酮注射液的治疗效果好,是一种在山羊血吸虫病治疗中可大力推广的药物。
Its curative effect is much better than that of praziquantel injection, so it is a kind of medicine that can be widely recommended for curing goats of schistosomiasis.
公司新建的广谱抗寄生虫原料药吡喹酮生产规模属国内最大,产品质量符合USP29/EP5。
The production scale of new constructed broad-spectrum anti-parasitosis bulk drug--- praziquantel is the largest one in our country, and the products quality complies with USP29/EP5.
根据肝细胞色素沉积特点及量的变化,可判断血吸虫病小鼠肝纤维化进程以及评判吡喹酮治疗效果。
Therefore, the degree of liver fibrosis in mice with schistosome infection and the effect of praziquantel can be recognized by the level and distribution of pigment.
吡喹酮能增强大白鼠离体心房和灌流心脏的心肌收缩力,与异搏定和心得安有一定程度的拮抗作用。
Experiments on the isolated atrium and perfused heart of rats showed that pyquiton (Praziquantel) had positive inotropic effect which can be antagonized by Propranolol and Verapamil.
目的观察慢性血吸虫病患者吡喹酮治疗前、后血清血吸虫肠相关趋阴极抗原(GACA)水平的变化。
Objective To observe the effect of praziquantel on the serum gut-associated cathodic antigen (GACA ) levels in the patients with chronic schistosomiasis before and after treatment.
在过去20年里,吡喹酮已被成功地用于在巴西、柬埔寨、中国、埃及、摩洛哥和沙特阿拉伯控制血吸虫病。
Praziquantel has been used successfully over the past 20 years to control schistosomiasis in Brazil, Cambodia, China, Egypt, Morocco and Saudi Arabia.
在过去20年里,吡喹酮已被成功地用于在巴西、柬埔寨、中国、埃及、摩洛哥和沙特阿拉伯控制血吸虫病。
Praziquantel has been used successfully over the past 20 years to control schistosomiasis in Brazil, Cambodia, China, Egypt, Morocco and Saudi Arabia.
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