低同源蛋白质的二级结构预测至今仍然是一个困难的问题。
Prediction of lowly homological protein secondary structure is still a difficult problem up to now.
在宿主-寄生虫疾病中,像结核病,非同源蛋白质作为药物靶点是首选。
In host-parasite diseases like Tuberculosis, non-homologous proteins as drug target are first preference.
大多数有效的药物靶点能够通过蛋白质相互作用网络分析,在大量非同源蛋白质间识别。
Most potent drug target can be identifying among large number of non-homologous protein through protein interaction network analysis.
证据表明,卫氏并殖吸虫的二倍体型和三倍体型虫株的蛋白质及其抗原性之间存在着高度的同源性。
The evidence demonstrated that there was extensive homology of the proteins and antigens between diploid and triploid Paragonimus westermani.
支持向量机是目前蛋白质远程同源检测应用最成功的方法。
Support Vector Machine is the most successful method of protein homology remote detection.
同源性分析表明该基因编码蛋白质可能具有肝片吸虫卵壳前体蛋白相似的性质和功能。
Homology analysis indicated that the protein is identical to the eggshell precursor protein of f.
我们的分类中的四个主要层次是蛋白质类(C),结构(A),拓扑结构(T)和同源超家族(H)。
The four main levels of our classification are protein class (c), architecture (a), topology (t) and homologous superfamily (h).
相反的,超过二十一种不同的血浆蛋白次单位可以组成血浆中双硫键键结的蛋白质同源体。
On the contrary, more than 21 different plasma protein subunits comprised the disulfide-mediated protein conjugates in plasma.
这些结果应该在下任何结论前被认真检查,因为很多陷阱在等待相似性搜索者:旁系同源物、多结构域蛋白质、假基因等。
These results should be carefully examined before coming to any conclusion, as many traps await the similarity seeker: paralogues, multidomain proteins, pseudogenes, etc.
在比较功能已知或未知蛋白质的结构同源性时,常常是根据氨基酸残基的疏水性或亲水性。
When the structural homology of proteins with known or unknown functions are compared, it is an usual way to base such comparisons on the hydrophobicity or hydrophilicity of the amino acid residues.
同源序列功能分类大致分为11类,与蛋白质合成有关的蛋白所占比例最大。
These ESTs were classified into 11 different functional categories, the highest proportion of which was related to protein synthesis.
我们在关于蛋白质亚细胞定位和远同源性检测的两个不同的数据集上做了实验。
We report experiments on two data sets, predicting subcellular localizations and remote homology detections.
对于多类蛋白质同源寡聚体分类,基于相同的机器学习方法(如支持向量机) ,采用“一对一”策略比“一对多”效果好。
Using "all-versus-all" policy is better than "one-versus-rest" policy for classifying homo-oligomers based on the same machine learning method (such as support vector machine).
对该特异性片段进行蛋白质序列比对,未发现与其于已知功能小麦片段有较高同源性。
The BLASTx analysis indicates that there are no wheat DNA fragments showing high homologous with the specific fragment.
本研究结果表明,卫氏并殖吸虫的二倍体型和三倍体型虫株的蛋白质及其抗原性之间存在着高度的同源性。
The evidence provided by this study demonstrated that there was extensive homology of the proteins and antigens between diploid and triploid Paragonimus westermani.
本文用支持向量机方法从蛋白质一级结构出发区分同源二聚体、同源三聚体、同源四聚体和同源六聚体。
Support vector machine approach is applied to classifying the homodimers, homotrimers, homotetramers and homohexamers from the primary structure.
通过互联网对测序获得的核苷酸序列进行同源性分析 ,并预测新基因编码蛋白质的结构与功能。
The positive clones were sequenced and the sequence data were analyzed using Nucleotide BLAST software of NCBI and Expert Protein Analysis System of Swiss Institute of Bioinformatics.
序列同源性分析表明,绵羊ttf - 1基因的核酸和蛋白质序列在不同哺乳动物之间有很高的同源性,分子在进化上均相当保守。
Homogeneous analysis demonstrated that nucleotide and amino acids sequences of sheep TTF-1 gene between different species mammal are comparatively conservative.
序列同源性分析表明,绵羊ttf - 1基因的核酸和蛋白质序列在不同哺乳动物之间有很高的同源性,分子在进化上均相当保守。
Homogeneous analysis demonstrated that nucleotide and amino acids sequences of sheep TTF-1 gene between different species mammal are comparatively conservative.
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