其他一些人,比如哈佛大学的GeorgeChurch,采取比较中间的位置,运用寡核苷酸芯片来合成个体基因成分,然后把它们拼在一起。
Others, like George Church of Harvard University, fall somewhere in the middle, synthesizing individual genetic components using oligonucleotide chips, then piecing them together.
目的合成异核苷掺入寡核苷酸并考察它们与互补序列的结合能力。
AimTo synthesize ribonucleoside-incorporated oligonucleotides and investigate their binding abilities with complementary sequences.
该机构为客户提供寡核苷酸合成、蛋白质测序、DNA测序、实时PCR和等位 基因检测等技术服务。
The facility provides technical services for the clients, which include Oligonucleotide Synthesis, Protein Sequencing, DNA Sequencing, Real Time PCR/Allele Detection.
应用聚合物支持合成多肽,寡核苷酸,并低聚糖是本文中介绍和讨论,鉴于它们的方法。
The application of polymer supports for the synthesis of polypeptides, oligonucleotides, and oligosaccharides is presented in this article and discussed in view of their methodology.
结果:MAPK反义寡核苷酸可明显抑制细胞活力、蛋白质含量、集落形成和DNA合成,其抑制率分别为52。6%、50。5%、54。9%和47。5%,与对照组比较差异有显著性(P<0。01)。
Results The cell viability, protein content, colony formation and DNA synthesis were significantly inhibited by MAPK ASO, the inhibitory rate was 52.6% , 50.5% , 54.9% and 47.5% respectively(P< 0.01).
方法:利用合成的寡核苷酸探针对60例慢性牙周炎患者60患病位点、10例健康人的10个对照位点龈下菌斑中伴放线菌放线杆菌进行检测。
Methods: Samples of subgingival plaque were detected for Aa distribution by oligonucleotide probe from 60 sites of CP patients and 10 healthy sites of healthy people.
根据肺炎支原体细胞粘附素蛋白质的基因保守区两侧序列,设计并合成一对变性寡核苷酸引物L2R2,用于以鸡毒支原体S6株基因组DNA为模板的PCR反应。
A pair of degenerate oligonucleotide primers named L2R2were synthesized according to conserved regions of the cytadhesin proteins from M. pneumonias. MG-S6DNA were used as model in L2R2 primered PCR.
本文总结了近十几年来立体控制性合成含手性磷酸酯基的寡核苷酸类似物的进展,重点介绍了寡核苷酸硫代磷酸酯和甲基膦酸酯的立体控制性合成方法。
In this review, the progress of stereocontrolled synthesis of P-chiral analogues of oligonucleotides was summarized with the emphasis on oligonucleotide phosphorothioates and methylphosphonates.
目的改进异鸟苷单体的合成路线 ,合成异鸟苷掺入的富鸟嘌呤的寡核苷酸。
Aim To improve the synthesis of isoguanosine monomer and to synthesize isoguanosine incorporated G-rich oligonucleotide.
目的改进异鸟苷单体的合成路线 ,合成异鸟苷掺入的富鸟嘌呤的寡核苷酸。
Aim To improve the synthesis of isoguanosine monomer and to synthesize isoguanosine incorporated G-rich oligonucleotide.
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