• 结论死亡引起应激诱导细胞保护基因HO - 1HSP70表达

    Conclusion the expression of the cytoprotective genes HO-1 and HSP70can be induced by renal stress caused by brains death.

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  • 目的建立一个诱导表达目的基因细胞系研究新基因的功能。

    Objective: to establish a stable cell line that can be induced to express a target gene.

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  • BDNF基因修饰的大鼠淋巴细胞培养上清降低H2O2DAPC 12细胞生长抑制并能抑制H2O2和DA诱导PC 12细胞凋亡

    ResultsThe supernatant of lymphocytes modified by BDNF gene decreased the growth inhibitory rate and apoptosis rate of PC12 cells induced by H2O2 and DA.

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  • 结论胸腺内注射基因MHC抗原诱导异体坐骨神经移植特异性免疫耐受

    Conclusion Intrathymus injection of allogene MHC antigen might induce specific immune tolerance to sciatic nerve allografts in mice.

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  • 磷酸化活化的丝裂原活化蛋白激酶,参与多种细胞生命活动调节基因转录诱导细胞凋亡、调节细胞周期

    The MAPK which activated through phosphorylation involve several cell life activities, just like the control gene transcription, induce cell death, regulate cell circle and so on.

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  • 激活低氧诱导因子(HIF - 1),从而调控一系列缺氧相关基因表达

    Hypoxia activates hypoxia-inducible factor 1 (HIF-1), thus it controls a series of expression of genes correlated with hypoxia.

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  • 结论FTY720体外呈时间依赖诱导正常大鼠gmc凋亡,其机制与影响细胞周期调节蛋白及凋亡相关基因表达有关。

    Conclusion FTY720 can induce GMC apoptosis in a time-dependent manner, probably through influencing gene expression of cell cycle regulatory proteins.

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  • 目的构建携带双自杀基因可诱导敲除SV40T逆转录病毒载体优化目前肝细胞生化。

    Objective To construct a new retroviral vector with double-suicide genes and knockout-inducible SV40T gene, with the aim of optimizing immortalization of hepatocytes.

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  • 诱导下,降解H细胞蛋白表达发生了变化,说明降解菌H中,参与菲降解的基因诱导的。

    The differential expression of whole cell protein of strain H induced by phenanthrene was very obvious. This indicated that gene clusters involved in phenanthrene degradation is inducible.

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  • 不仅提高肝胰腺卵黄蛋白原基因表达水平诱导雄性中华绒螯肝胰腺vtg基因的表达。

    Not only to enhance the VTG gene expression level in female carb, but also can induce VTG gene expression in the male crab.

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  • 结论IL - 6启动作为一种诱导型启动子在树突状细胞内发挥活性,因而有望用于基因治疗基因功能研究

    Conclusion IL-6 promoter can be used as an inducible promoter in researches of gene therapy and gene function.

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  • 结论:异种血管内皮生长因子基因重组T7噬菌体疫苗打破机体自身vegf免疫耐受,诱导产生较高水平的特异性抗vegf抗体

    Conclusion: Recombinant T7 phage vaccine expressing xenogenic VEGF can break immunologic tolerance against self-VEGF and induce the producing of specific anti-VEGF antibody.

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  • UVB辐射诱导机体产生活性氧自由基,从而引起细胞生物学改变,导致基因突变致癌细胞死亡

    UVB irradiation can induce the formation of reactive oxygen species (ROS), and induce the change of cell biology, gene mutation, carcinogenesis and cell death.

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  • 为了研究Lrp5如何影响特性我们建立了骨细胞特异性表达诱导型Lrp5基因突变小鼠,该基因突变导致人类骨量表型

    To understand how Lrp5 influences bone properties, we generated mice with osteocyte-specific expression of inducible Lrp5 mutations that cause high and low bone mass phenotypes in humans.

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  • 利用这种诱导调控系统用于定量调控基因表达以及进行毒性基因功能分析方面的研究。

    Using this inducible system can be used for quantitative regulation of gene expression regulation and virulence gene function analysis and so on.

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  • 实验结果表明联合应用自杀基因细胞因子基因治疗更有效诱导机体肿瘤免疫反应,从而更显著抑制荷瘤小鼠肿瘤生长

    Our results demonstrated that combined transfer of suicide gene and IL-2 gene could inhibit the growth of established tumor in mice significantly and induce antitumor immunity of the host efficiently.

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  • 实验结果表明联合应用自杀基因细胞因子基因治疗更有效诱导机体肿瘤免疫反应,从而更显著抑制荷瘤小鼠肿瘤生长

    Our results demonstrated that combined transfer of suicide gene and IL-2 gene could inhibit the growth of established tumor in mice significantly and induce antitumor immunity of the host efficiently.

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