结论脑死亡引起的肾应激可诱导细胞保护基因HO - 1和HSP70的表达。
Conclusion the expression of the cytoprotective genes HO-1 and HSP70can be induced by renal stress caused by brains death.
目的:建立一个可诱导表达目的基因的细胞系以研究新基因的功能。
Objective: to establish a stable cell line that can be induced to express a target gene.
BDNF基因修饰的大鼠淋巴细胞的培养上清可降低H2O2和DA对PC 12细胞生长的抑制率并能抑制H2O2和DA诱导PC 12细胞凋亡。
ResultsThe supernatant of lymphocytes modified by BDNF gene decreased the growth inhibitory rate and apoptosis rate of PC12 cells induced by H2O2 and DA.
结论胸腺内注射异基因MHC抗原可诱导大鼠对异体坐骨神经移植的特异性免疫耐受。
Conclusion Intrathymus injection of allogene MHC antigen might induce specific immune tolerance to sciatic nerve allografts in mice.
经磷酸化活化的丝裂原活化蛋白激酶,可参与多种细胞生命活动,如调节基因转录,诱导细胞凋亡、调节细胞周期等。
The MAPK which activated through phosphorylation involve several cell life activities, just like the control gene transcription, induce cell death, regulate cell circle and so on.
低氧可激活低氧诱导因子(HIF - 1),从而调控一系列与缺氧相关基因的表达。
Hypoxia activates hypoxia-inducible factor 1 (HIF-1), thus it controls a series of expression of genes correlated with hypoxia.
结论FTY720在体外可呈时间依赖诱导正常大鼠gmc凋亡,其机制与影响细胞周期调节蛋白及凋亡相关基因的表达有关。
Conclusion FTY720 can induce GMC apoptosis in a time-dependent manner, probably through influencing gene expression of cell cycle regulatory proteins.
目的构建携带双自杀基因且可诱导敲除SV40T的逆转录病毒载体,优化目前的肝细胞永生化。
Objective To construct a new retroviral vector with double-suicide genes and knockout-inducible SV40T gene, with the aim of optimizing immortalization of hepatocytes.
在菲诱导下,降解菌H的全细胞蛋白的表达发生了变化,说明在降解菌H中,参与菲降解的基因是可诱导的。
The differential expression of whole cell protein of strain H induced by phenanthrene was very obvious. This indicated that gene clusters involved in phenanthrene degradation is inducible.
不仅可提高雌蟹肝胰腺中卵黄蛋白原基因的表达水平,也可诱导雄性中华绒螯蟹肝胰腺vtg基因的表达。
Not only to enhance the VTG gene expression level in female carb, but also can induce VTG gene expression in the male crab.
结论IL - 6启动子可作为一种可诱导型启动子在树突状细胞内发挥活性,因而有望用于基因治疗或基因功能研究。
Conclusion IL-6 promoter can be used as an inducible promoter in researches of gene therapy and gene function.
结论:异种血管内皮生长因子基因重组T7噬菌体疫苗可打破机体对自身vegf的免疫耐受,诱导产生较高水平的特异性抗vegf抗体。
Conclusion: Recombinant T7 phage vaccine expressing xenogenic VEGF can break immunologic tolerance against self-VEGF and induce the producing of specific anti-VEGF antibody.
UVB辐射可诱导机体产生活性氧自由基,从而引起细胞生物学改变,导致基因突变、致癌和细胞死亡。
UVB irradiation can induce the formation of reactive oxygen species (ROS), and induce the change of cell biology, gene mutation, carcinogenesis and cell death.
为了研究Lrp5如何影响骨特性,我们建立了骨细胞特异性表达诱导型Lrp5基因突变的小鼠,该基因突变可导致人类高和低骨量表型。
To understand how Lrp5 influences bone properties, we generated mice with osteocyte-specific expression of inducible Lrp5 mutations that cause high and low bone mass phenotypes in humans.
利用这种可诱导的调控系统可以用于定量调控基因表达以及进行毒性基因功能分析等方面的研究。
Using this inducible system can be used for quantitative regulation of gene expression regulation and virulence gene function analysis and so on.
实验结果表明,联合应用自杀基因与细胞因子基因治疗可更有效诱导机体的抗肿瘤免疫反应,从而更显著地抑制荷瘤小鼠肿瘤的生长。
Our results demonstrated that combined transfer of suicide gene and IL-2 gene could inhibit the growth of established tumor in mice significantly and induce antitumor immunity of the host efficiently.
实验结果表明,联合应用自杀基因与细胞因子基因治疗可更有效诱导机体的抗肿瘤免疫反应,从而更显著地抑制荷瘤小鼠肿瘤的生长。
Our results demonstrated that combined transfer of suicide gene and IL-2 gene could inhibit the growth of established tumor in mice significantly and induce antitumor immunity of the host efficiently.
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