俄亥俄州立大学的微生物学家阿布罕·萨托斯卡和他的同事研制了一种新药,给II型糖尿病小鼠口服后可以控制其症状。
A new drug studied by Abhay Satoskar, a microbiologist at Ohio State University, and his colleagues can control the symptoms of type 2 diabetes in mice when taken orally.
口语中生物有效性的意思是:口服的某种药或者某种物质可以被身体吸收和利用。
Orally bioavailable means that a drug or other substance that is taken by mouth can be absorbed and used by the body.
这些给药系统的口服制剂的组成和与药物相关的生物药剂学方面已经进行了广泛的研究。
The formulation and drug-related biopharmaceutical aspects of these systems that govern oral absorption have been widely studied.
目的建立以微生物比浊法测定口服阿奇霉素效价含量的方法。
OBJECTIVE To establish a method for determining the microbial assays of oral azithromycin by turbidimetric method.
结论:壳聚糖- CEC双层包覆胰岛素脂质体有利于改善胰岛素口服生物利用度。
CONCLUSION: The insulin-liposomes double-coated with chitosan and CEC were in favor of improving oral bioavailability of insulin.
结果药物的溶解性、稳定性、膜通透性和首过作用等生物药剂学性质是影响药物口服后经胃肠道吸收的主要因素。
Results The solubility, stability in gastrointestinal tract, membrane permeability and presystemic metabolism of drugs were the major factors on oral drug absorption.
前药研究是提高生物药剂学分类系统中第III和IV类药物口服吸收的有效途径之一。
Prodrug is an effective way to improve the oral absorption of the drugs which belong to Biopharmaceuticals Classification System(BCS) class III and IV.
目的:研究国产盐酸托烷司琼胶囊与进口注射液口服给药后的人体相对生物利用度。
OBJECTIVE To study the pharmacokinetics and relative bioavailability of tropisetron hydrochloride domestic capsule and imported injection in healthy volunteers.
目的介绍FDA关于普通口服固体制剂生物等效豁免的相关政策。
Objective To introduce FDA's biowaiver policy for IR solid oral dosage forms.
从生物药剂学的角度设计了“半仿生提取法”制备中药口服制剂的新工艺。
In the light of biopharmacy, the present new technology to extract oral preparations of Chimese traditional medicinal by semi-bionic method was designed.
本工作将SOD制成微球,以提高SOD稳定性和口服相对生物利用度,且在微球制备条件方面作了进一步研究。
In this work, SOD gelatin microspheres were made with the aim to improve its stability, oral relative bioavailability, and to study the preparation conditions of microspheres.
目的介绍WHO关于口服仿制药生物等效豁免的相关政策。
Objective To introduce WHO's biowaiver policy for oral generic drugs.
人胎素口服液由健康胎盘和多味优质药材科学组方,经现代生物技术工程精制而成。
It is using the healthy placenta and many kinds of high quality raw materials for Chinese medicine scientific formula after modern biological technology project fine manufacture.
口服阿苯达唑脂质体有较高的生物利用度并有一定的肝脏靶向性。
Oral albendazole liposomes has shown higher bioavailability and liver targeting in comparison with tablet formulation.
吸收过程是决定口服药物生物利用度的重要因素,然而很多药物的吸收机制还不明确。
The absorption process is an important factor in determining the bioavailability of orally administered drugs. however, the absorption mechanism of many drugs is not clear.
目的研制一种生物利用度高适合餐后血糖变化模式的胰岛素口服制剂。
Objective To manufacture a high bioavailability oral insulin that fit the blood glucose change after meals.
开发口服型的GLP-1药物存在许多难题,尤其是需要有足够的生物利用度。
There are many challenges in developing an oral formulation of GLP-1, in particular obtaining adequate bioavailability.
背景:法莫替丁作为组胺H_2受体拮抗剂,其口服吸收不完全,生物利用度约为37% - 50%。
Background: As one of the histamine H_2 receptor antagonist, the oral absorption of famotidine is not complete, its bioavailability is about 37%-50%.
胃肠道生物粘附给药系统(GBDDS)是现代生物粘附技术在口服制剂中的运用。
Gastrointestinal bioadhesion drug delivery system (GBDDS) can be considered as an application of bioadhesion technology to the oral drug delivery system.
FP的口服制剂中,大多存在溶出难和生物利用度低的问题。
Most oral dosage forms of FP had low bioavailability because FP could hardly dissolve.
目的综述药物的生物药剂学性质对药物口服吸收的影响。
Objective To review the impacts of biopharmaceutical characteristics on oral drug absorption.
自乳化药物传递系统可显著地提高难溶性或亲脂性药物口服生物利用度,具有广阔的发展前景。
The SEDDS can dramatically improve the bioavailability of poorly water soluble or lipophilic drugs by oral administration. SEDDS will have a good developmental potential.
PTK787因其对肿瘤抑制的出色疗效、口服生物利用度高等特点而成为VEGF受体酪氨酸激酶抑制剂中的佼佼者。
PTK787 is the most promising VEGF receptor- tyrosine kinase inhibitor in pipeline because of its potency in tumor inhibition and oral bioavailability.
前言:目的:确认所采用的方法适合于葡萄糖酸钙口服溶液的微生物限度检查计数方法。
Objective: the confirmation USES the method suits in the microorganism of the calcium gluconate oral solution limit inspection technology method.
炔雌醇口服生物利用度低,有胃肠道副作用,日给药次数多。
This drug has low bioavailability, adverse reaction of gastrointestinal tract by oral administration, and is administered frequency.
讨论了影响自胃肠道吸收药物生物利用度的因素,对提高难溶性药物口服生物利用度的方法进行了综述。
Factors that affect the oral bioavailability of water insoluble drugs were discussed, and a review was given on the measures of improving the oral bioavailability of water insoluble drugs.
目的制备缓释胸腺肽口服片剂,并探讨其生物学活性及对小鼠免疫功能的影响。
Objective To prepare oral control-released thymopoietin (TP) tablet and explore its bioactivity as well as its effect on the immune function of mice.
目的制备缓释胸腺肽口服片剂,并探讨其生物学活性及对小鼠免疫功能的影响。
Objective To prepare oral control-released thymopoietin (TP) tablet and explore its bioactivity as well as its effect on the immune function of mice.
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