• 两种基因产生与上述受体结合大量蛋白压制削弱有功能肌肉生长抑制素分子作用

    These churn out proteins which bind to the receptors, swamping and diluting the effect of functional myostatin molecules.

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  • 基因编码一种蛋白被称为趋化因子受体CXCR4同样有助于艾滋病毒感染免疫细胞

    The gene codes for a protein, also called CXCR4, that also helps HIV infect immune cells.

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  • 研究人员一段他们进行基因编码基因重组病毒感染T细胞,基因编码是能够识别黑色素瘤细胞的受体蛋白的。

    They did this by infecting the T-cells with genetically modified viruses carrying genes that coded for receptors to melanoma molecules.

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  • 是否应该是 缺少关爱老鼠糖皮质激素受体基因 基因周边蛋白表现出水平甲基较低水平的乙酰化。 另,acetylation 是否应该是乙醇化?

    Rats that had experienced little maternal care showed high levels of methylation and low levels of acetylation of the glucocorticoid-receptor gene and its neighbouring proteins.

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  • 他们发现称为多巴D2受体DRD2)的分子基因差异,DRD2受体脑细胞神经递质多巴胺敏感的一种蛋白

    They found the differences in the gene for a molecule called the dopamine D2 receptor (DRD2), a protein present on brain cells that are sensitive to the neurotransmitter dopamine.

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  • 十多年取得了重大进展,加州生物科技公司Genentech(中文名:基因泰克)发行了一种药物,这种药物攻击蛋白HER2(中文名:人表皮生长因子受体- 2)含量过多乳腺癌细胞

    A breakthrough came more than a decade ago when Genentech, a Californian biotech firm, launched a drug that attacks breast-cancer cells with too much of a certain protein, HER2.

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  • 结论:染料木黄酮不是通过促进雌激素受体基因蛋白表达促进成骨细胞增殖

    CONCLUTION Genistein promotes the proliferation of osteoblast not through promoting the expression of estrogen receptor gene and protein.

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  • 为了了解LXR如何调节低密度脂蛋白受体作者研究了LXR基因转录确定一个编码肌球蛋白互动蛋白基因IDOL

    To understand how LXR regulates LDLR, the authors examined transcriptional target genes of LXR and identified a gene that encodes a myosin interacting protein, IDOL.

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  • 目的:研究人外周血淋巴细胞黑素受体(MR)的基因蛋白表达特点。

    AIM: to investigate the melatonin receptor (MR) gene and protein expression in the human peripheral blood lymphocytes.

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  • 目的观察肝细胞瘦素受体蛋白基因表达酪氨酸磷酸化影响

    Objective to investigate effects of leptin on gene and protein expression and tyrosine phosphorylation of leptin receptor in rat hepatocytes.

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  • 构建小鼠il -4短型基因真核表达表达小鼠il - 4受体抗体蛋白

    To clone mouse interleukin 4 (mIL-4) truncated gene, construct its eukaryotic expression plasmid pFB-mIL4 and express the truncated protein (murine IL-4 receptor antagonist).

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  • 目的检测杀伤免疫球蛋白受体(KIR)基因广东汉族人群中的分布

    Objective to investigate the distribution of killer immunoglobulin-like receptor (KIR) gene in Guangdong Han population.

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  • 目的探讨中国北方绝经妇女低密度蛋白受体相关蛋白5LRP5基因Q89RA1330V多态性骨密度关系。

    Objective To investigate the association of lipoprotein receptor-related protein 5(LRP5) gene Q89R, A1330V polymorphism with bone mineral density(BMD) in premenopausal Northern Chinese women.

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  • 新的肿瘤相关基因,其结构上受体蛋白相似具有一个蛋白激酶结构

    Novel Oncogene with Kinase-domain (NOK) is a novel tumor-related gene, coding receptor like protein with a kinase domain.

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  • HR蛋白细胞核受体阻遏物发现证明HR蛋白是通过毛发周期调节基因表达来发挥作用的。

    The discovery that the HR protein is a nuclear receptor corepressor indicated that HR function in hair cycling is by regulating gene expression.

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  • 目的克隆人甲状腺激素受体胞外段基因构建重组真核表达质粒,获得具有免疫学活性纯化重组蛋白

    Objective to clone and construct the plasmid containing human thyroid stimulating hormone receptor (TSHR) gene ectodomain, and then identify the immunoreactivity of the purified recombinant protein.

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  • 转录最高的基因功能相关,细胞粘附基质蛋白生长因子受体蛋白

    The most highly transcribed genes relate to functional groupings such as cell adhesion, matrix proteins, growth factors and receptors, and proteases.

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  • 免疫组化流式细胞术检测肾脏TRAIL基因及其死亡受体DR 4、DR5蛋白表达

    Immunohistochemistry and FCM were used to detect the expression of TRAIL and its death receptors (DR4 and DR5).

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  • 目的观察表皮生长因子受体EGFR口腔复发性阿弗他溃疡(RAU) 组织中蛋白基因表达变化

    Objective To explore the expression change of protein and mRNA of EGFR(epidermal growth factor receptor)in RAU(recurrent aphthous ulcer).

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  • 其与甲状腺发育有关,并且调控甲状腺球蛋白、甲状腺过氧化物酶促甲状腺激素受体基因转录

    TTF-1 is related to development of the thyroid gland and regulates and controls transcriptions of thyroglobulin(TG), thyroperoxidase(TPO), and thyrotropin(TSH) receptor genes.

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  • 化合物筛选高效率基因指纹技术进步微阵列技术蛋白质组学加速有效选择性受体调节子鉴定

    Advancement in high throughput compound screening and gene fingerprinting technologies, such as microarrays and proteomics, will facilitate and accelerate identification of effective SARMs.

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  • 低密度蛋白受体相关蛋白5 (LRP5)基因突变可影响人体骨骼

    The human skeleton is affected by mutations in low-density lipoprotein receptor-related protein 5 (LRP5).

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  • 受体是一类蛋白全长蛋白很难通过基因工程获得,这制备该类蛋白的抗体增加了难度。

    Membrane receptors belong to a kind of membrane proteins, the full length protein of which is hard to be expressed in vitro.

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  • 这个变异称为IVS5-13insC,造成HMGA1蛋白功能损伤,HMGA1蛋白调节胰岛素受体基因INSR表达的辅助因子。

    The variant, designated IVS5-13insC, impairs function of the HMGA1 protein, a cofactor for gene activation that regulates insulin-receptor gene (INSR) expression.

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  • 而且钙化心肌细胞受体活性修饰蛋白2和肾上腺髓质素基因表达上调程度平行

    The elevated level of RAMP2 mRNA was parallel to that of ADM mRNA in calcified myocardial cells.

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  • 目的观察中毒对神经细胞尼古丁受体亚单位蛋白基因表达水平影响氟中毒引起尼古丁受体功能改变发生机制

    Objective to investigate the influence of fluorosis on nicotinic acetylcholine receptors (nAChRs) in protein and gene levels in SH-SY5Y cells and the mechanism of the receptor modification.

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  • 发明公开了通过应用辅助基因表达来实现改进G蛋白受体功能分析方法

    Disclosed herein are methods for enabling or improving functional assays of G-protein coupled receptors through the use of co-expression of helper genes.

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  • 发明公开了通过应用辅助基因表达来实现改进G蛋白受体功能分析方法

    Disclosed herein are methods for enabling or improving functional assays of G-protein coupled receptors through the use of co-expression of helper genes.

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