这两种基因产生与上述受体结合的大量蛋白质,压制和削弱有功能肌肉生长抑制素分子的作用。
These churn out proteins which bind to the receptors, swamping and diluting the effect of functional myostatin molecules.
该基因编码的一种蛋白质,也被称为趋化因子受体CXCR4,同样有助于艾滋病毒感染免疫细胞。
The gene codes for a protein, also called CXCR4, that also helps HIV infect immune cells.
研究人员用一段被他们进行基因编码的基因重组病毒感染T细胞,这段基因编码是能够识别黑色素瘤细胞的受体蛋白的。
They did this by infecting the T-cells with genetically modified viruses carrying genes that coded for receptors to melanoma molecules.
是否应该是 缺少关爱的老鼠糖皮质激素受体基因和 基因周边的蛋白质表现出高水平的甲基化及较低水平的乙酰化。 另,acetylation 是否应该是乙醇化?
Rats that had experienced little maternal care showed high levels of methylation and low levels of acetylation of the glucocorticoid-receptor gene and its neighbouring proteins.
他们发现了一个称为多巴胺D2受体(DRD2)的分子的基因差异,DRD2受体是人脑细胞上对神经递质多巴胺敏感的一种蛋白质。
They found the differences in the gene for a molecule called the dopamine D2 receptor (DRD2), a protein present on brain cells that are sensitive to the neurotransmitter dopamine.
十多年前就取得了重大进展,一个加州的生物科技公司Genentech(中文名:基因泰克)发行了一种药物,这种药物攻击蛋白质HER2(中文名:人表皮生长因子受体- 2)含量过多的乳腺癌细胞。
A breakthrough came more than a decade ago when Genentech, a Californian biotech firm, launched a drug that attacks breast-cancer cells with too much of a certain protein, HER2.
结论:染料木黄酮不是通过促进雌激素受体基因和蛋白的表达来促进成骨细胞增殖。
CONCLUTION Genistein promotes the proliferation of osteoblast not through promoting the expression of estrogen receptor gene and protein.
为了了解LXR如何调节低密度脂蛋白受体,作者研究了LXR靶基因的转录,并确定了一个能编码肌球蛋白互动蛋白的基因,IDOL。
To understand how LXR regulates LDLR, the authors examined transcriptional target genes of LXR and identified a gene that encodes a myosin interacting protein, IDOL.
目的:研究人外周血淋巴细胞褪黑素受体(MR)的基因与蛋白表达的特点。
AIM: to investigate the melatonin receptor (MR) gene and protein expression in the human peripheral blood lymphocytes.
目的观察瘦素对大鼠肝细胞瘦素受体蛋白、基因表达及酪氨酸磷酸化的影响。
Objective to investigate effects of leptin on gene and protein expression and tyrosine phosphorylation of leptin receptor in rat hepatocytes.
构建小鼠il -4截短型基因真核表达质粒,表达小鼠il - 4受体拮抗体蛋白。
To clone mouse interleukin 4 (mIL-4) truncated gene, construct its eukaryotic expression plasmid pFB-mIL4 and express the truncated protein (murine IL-4 receptor antagonist).
目的检测杀伤免疫球蛋白样受体(KIR)基因在广东汉族人群中的分布。
Objective to investigate the distribution of killer immunoglobulin-like receptor (KIR) gene in Guangdong Han population.
目的探讨中国北方绝经前妇女低密度脂蛋白受体相关蛋白5(LRP5)基因Q89R、A1330V多态性与骨密度关系。
Objective To investigate the association of lipoprotein receptor-related protein 5(LRP5) gene Q89R, A1330V polymorphism with bone mineral density(BMD) in premenopausal Northern Chinese women.
是一个新的肿瘤相关基因,其结构上与受体蛋白相似,具有一个蛋白激酶结构域。
Novel Oncogene with Kinase-domain (NOK) is a novel tumor-related gene, coding receptor like protein with a kinase domain.
HR蛋白是细胞核受体辅阻遏物的发现证明HR蛋白是通过在毛发周期中调节基因表达来发挥作用的。
The discovery that the HR protein is a nuclear receptor corepressor indicated that HR function in hair cycling is by regulating gene expression.
目的克隆人促甲状腺激素受体胞外段基因,构建重组真核表达质粒,获得具有免疫学活性的纯化重组蛋白。
Objective to clone and construct the plasmid containing human thyroid stimulating hormone receptor (TSHR) gene ectodomain, and then identify the immunoreactivity of the purified recombinant protein.
转录最高的基因与功能相关,如细胞粘附,基质蛋白,生长因子,受体和蛋白酶。
The most highly transcribed genes relate to functional groupings such as cell adhesion, matrix proteins, growth factors and receptors, and proteases.
免疫组化和流式细胞术检测肾脏TRAIL基因及其死亡受体DR 4、DR5的蛋白表达。
Immunohistochemistry and FCM were used to detect the expression of TRAIL and its death receptors (DR4 and DR5).
目的观察表皮生长因子受体(EGFR)在口腔复发性阿弗他溃疡(RAU) 组织中蛋白和基因表达变化。
Objective To explore the expression change of protein and mRNA of EGFR(epidermal growth factor receptor)in RAU(recurrent aphthous ulcer).
其与甲状腺的发育有关,并且调控甲状腺球蛋白、甲状腺过氧化物酶和促甲状腺激素受体基因的转录。
TTF-1 is related to development of the thyroid gland and regulates and controls transcriptions of thyroglobulin(TG), thyroperoxidase(TPO), and thyrotropin(TSH) receptor genes.
化合物筛选的高效率和基因指纹技术的进步,如微阵列技术和蛋白质组学,将加速有效的选择性受体调节子鉴定。
Advancement in high throughput compound screening and gene fingerprinting technologies, such as microarrays and proteomics, will facilitate and accelerate identification of effective SARMs.
低密度脂蛋白受体相关蛋白5 (LRP5)基因突变可影响人体骨骼。
The human skeleton is affected by mutations in low-density lipoprotein receptor-related protein 5 (LRP5).
膜受体是一类膜蛋白,而全长的膜蛋白很难通过基因工程获得,这给制备该类蛋白的抗体增加了难度。
Membrane receptors belong to a kind of membrane proteins, the full length protein of which is hard to be expressed in vitro.
这个变异称为IVS5-13insC,造成HMGA1蛋白的功能损伤,HMGA1蛋白是调节胰岛素受体基因(INSR)表达的辅助因子。
The variant, designated IVS5-13insC, impairs function of the HMGA1 protein, a cofactor for gene activation that regulates insulin-receptor gene (INSR) expression.
而且钙化心肌细胞受体活性修饰蛋白2和肾上腺髓质素基因表达上调的程度相平行。
The elevated level of RAMP2 mRNA was parallel to that of ADM mRNA in calcified myocardial cells.
目的观察氟中毒对神经细胞中尼古丁受体亚单位蛋白和基因表达水平的影响及氟中毒引起尼古丁受体功能改变的发生机制。
Objective to investigate the influence of fluorosis on nicotinic acetylcholine receptors (nAChRs) in protein and gene levels in SH-SY5Y cells and the mechanism of the receptor modification.
本发明公开了通过应用辅助基因的共表达来实现或改进G蛋白偶联受体的功能分析的方法。
Disclosed herein are methods for enabling or improving functional assays of G-protein coupled receptors through the use of co-expression of helper genes.
本发明公开了通过应用辅助基因的共表达来实现或改进G蛋白偶联受体的功能分析的方法。
Disclosed herein are methods for enabling or improving functional assays of G-protein coupled receptors through the use of co-expression of helper genes.
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