是一个新的肿瘤相关基因，其结构上与受体蛋白相似，具有一个蛋白激酶结构域。
Novel Oncogene with Kinase-domain (NOK) is a novel tumor-related gene, coding receptor like protein with a kinase domain.
目的：研究散发型甲状腺髓样癌酪氨酸激酶受体基因（RET）的突变情况。
Objective:To explore the mutation of receptor tyrosine kinase ( RET ) gene in sporadic medullary thyroid carcinoma.
目的：探讨表皮生长因子受体(EGFR)基因酪氨酸激酶域体细胞在肺腺癌患者中突变的相关因素。
Objective: to study Somatic mutation of the tyrosine kinase (TK) domain of the epidermal growth factor receptor (EGFR gene) in lung adenocarcinoma patients.
经过分类分析，下调基因，主要可以分为五个功能类：蛋白质降解、RNA转录调控、细胞壁合成降解、激酶受体和肽运输。
The down-regulated genes can be divided in five classes:protein degradation, RNA transcription, cell wall synthesis and degradation, kinase receptor and peptide transport.
方法：对原发性高血压伴胰岛素抵抗患者胰岛素受体基因酪氨酸激酶域外显子17、18基因突变进行检测，并对突变的外显子进行核苷酸序列分析。
Methods: Using PCR SSCP, we detected the mutation of INSR tyrosine kinase domain exon 17 and exon 18 in 33 primary hypertension patients and 28 normal persons.
方法：对原发性高血压伴胰岛素抵抗患者胰岛素受体基因酪氨酸激酶域外显子17、18基因突变进行检测，并对突变的外显子进行核苷酸序列分析。
Methods: Using PCR SSCP, we detected the mutation of INSR tyrosine kinase domain exon 17 and exon 18 in 33 primary hypertension patients and 28 normal persons.
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