“从不吸烟的患者对一类叫表皮生长因子受体抑制剂的药物反应更好，因为这类患者有表皮生长因子受体基因突变的可能性更大一些。”鲁丁说。
"Patients who never smoked respond better to a certain class of drugs called EGFR inhibitors, because lung cancer in these patients more often contain mutations in the EGFR gene," Rudin says.
比较了冷应激后胃对SP和SP受体拮抗剂的动力学反应性的变化。
We also identified the change in gastrokinetic reaction to SP and SP receptor antagonist after cold stress.
结论TMP主要通过抑制P 2 X受体兴奋介导的伤害性信息传递产生抗伤害性反应作用。
Conclusion the antinociceptive effects of TMP may mainly be associated with inhibiting the transmission of nociceptive information mediated by P2X receptor activation.
自然杀伤细胞通过其表达的不同类型的受体选择性识别细胞表面的相应配体，提供自然杀伤细胞反应的自我调节信号。
Different types of receptors expressed by natural killer (NK) cells may selectively recognize their specific ligands on some other cells and provide self-regulatory signals to control NK responses.
结论：缬沙坦可能是通过抑制AT 1受体抑制哮喘气道炎症和降低气道反应性。
Conclusion: Valsartan may inhibit airway inflammation and reduce airway responsiveness by suppressing AT1 receptors.
CRF对豚鼠结肠肌间神经丛有很强的兴奋作用，可诱发慢的兴奋性去极化反应，而且CRF所兴奋的神经元均为表达CRF1受体的神经元。
CRF could evoke a slowly activating depolarizing response that associated with enhanced excitability in myenteric neurons in colon. The cells excited by CRF were all expressed with CRF1 receptor.
目的本研究旨在观察沙坦类药物代谢酶CYP2C9和反应受体AT1的遗传多态性在高血压患者中的分布特征。
Objective To investigate the genetic polymorphism of sartan drug metabolic enzyme CYP2C9 and angiotensin AT1 receptor in hypertensive patients.
ChristopherGarcia领衔的科研小组揭示了T细胞表面受体结构为何能双重识别，该现象也称为同种异体反应性。
Christopher Garcia have established how the structure of receptors on the surface of t cells enables this dual recognition, a phenomenon known as alloreactivity.
结论HIC呈内毒素无反应性，其表面内毒素相关受体tlr4、CD 14和MD 2不表达是其耐受内毒素作用的重要分子机制。
Conclusion There was no response of HICs to LPS stimulation, and no expression of TLR4, CD14 and MD-2 on HICs may be an important molecular mechanism by which they tolerated to lipopolysaccharide.
人群中DNA存在多态性，与药物反应相关的基因多态性可能产生药物效应的个体差异，例如药物代谢酶、药物作用受体以及其它一些与疾病相关基因等。
Polymorphisms exist in human genomic DNA. And some polymorphisms such as metabolic enzymes, drug receptors, and some other genes correlated with diseases may affect the drug responsiveness.
如这类反应是发生在雌激素依赖性肿瘤细胞内的雌激素受体上，可能会有抑制肿瘤生长的作用。
If these reactions occurred on the estrogen receptors in the cells of estrogen-dependent tumors, the growth of tumors may be inhibited.
由于对受体的选择性不高，绝大多数中药单体提取物引起的PD反应复杂多样。
As a low selectivity in the receptors, most PD reactions from Chinese herbal monomer extracts turn out to be diversified.
兔单抗能够识别内源性水平的总FGF受体2蛋白。该抗体不与其他FGF受体家族成员发生交叉反应。
FGF receptor 2 (D4H9) Rabbit mAb recognizes endogenous levels of total FGF receptor 2 protein. This antibody does not cross-react with other FGF receptor family members.
方法采用聚合酶链式反应-单链构象多态性方法检测46例高血压患者和39例正常血压对照者的胰岛素受体基因第17、18外显子的多态性。
Methods The polymorphism if exon 17 and 18 of insulin gene were detected in 46 hypertension patients and 39 normal controls using PCR and single strand conformation polymorphism.
结论：RSV感染导致气道副交感神经自身抑制性M2受体功能障碍，引起气道高反应性发生。
CONCLUSION: These results indicate that RSV infection can cause dysfunction of M2 autoreceptor on the airway preganglionic cholinergic nerves, resulting in airway hyperresponsiveness.
结论：RSV感染导致气道副交感神经自身抑制性M2受体功能障碍，引起气道高反应性发生。
CONCLUSION: These results indicate that RSV infection can cause dysfunction of M2 autoreceptor on the airway preganglionic cholinergic nerves, resulting in airway hyperresponsiveness.
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