本研究确定了主要的组蛋白h 2 A去泛素和表明H2A去泛素化是至关重要参与细胞周期进程和基因表达。
This study identifies the major deubiquitinase for histone H2A and demonstrates that H2A deubiquitination is critically involved in cell cycle progression and gene expression.
去核时卵母细胞质剩得过少可导致移核胚过早(6-细胞期)发生致密化或形成内细胞团细胞数目较少的小囊胚;
Too much reduction of the cytoplasmic mass at enucleationled to premature compaction of the nuclear transplant embryos at 6-cell stage or the formation of small blastocysts with few ICM cells;
氮-2'-脱氧胞苷等去甲基化药物作为抗肿瘤药物的效应,归因于两种机制:细胞毒性和诱导低甲基化。
The efficacy of hypomethylating agents (e. g. 5 aza 2′ deoxycytidine) as antineoplastic agents has been attributed to two distinct mechanism: cytotoxicity and induction of hypomethylation.
嗅鞘细胞在移植治疗轴突损伤和去髓鞘化疾病的研究中显示出潜在的临床应用前景。
OEC transplantation has emerged as a promising experimental therapy of axonal injuries and demyelinating diseases.
嗅鞘细胞在移植治疗轴突损伤和去髓鞘化疾病的研究中显示出潜在的临床应用前景。
OEC transplantation has emerged as a promising experimental therapy of axonal injuries and demyelinating diseases.
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