自从牛睾丸中提取出一种水溶性物,并发现可以抑制肥大的垂体去势细胞而命名为抑制素以来,关于抑制素的研究已有70余年的历史。
Inhibin is a kind of material with water-solubility from bull testicular, of which the name arises from its effect in inhibiting castration cells in pituitary.
目的探讨去势雄兔干眼病模型角膜上皮细胞凋亡及相关基因表达与组织损伤的关系。
Objective to assess corneal epithelial cell apoptosis and related gene expression in castrated male rabbit with experimental xerophthalmia.
结论:FSH细胞内液泡及其内含物与去势有关,可能为FSH细胞功能衰竭状态的特征性改变。
Conclusion: FSH cell vacuole and its contents were related to castration. It may be the characteristic change of function consumption of FSH cells.
结果:去势雌性大鼠血脂代谢紊乱,主动脉平滑肌细胞雌激素受体水平下降。
Results: The disorder of serum lipid and the decrease of the level of estrogen receptors in the vascular smooth muscle cells were found in the ovariectomized female rats.
目的:探讨雌二醇、孕酮对去势小鼠外周血白细胞和淋巴细胞的调节。
Objective: to investigate the regulation of estradiol and progesterone on leukocyte and lymphocyte of peripheral blood in ovariectomized mice.
明确地说,该研究团队发现,在对心脏移植努力产生免疫耐受的老迈小鼠中,对其进行去势手术可导致其机体长期地接受移植物并恢复胸腺细胞的产生。
Specifically, in elderly mice struggling to develop tolerance to cardiac transplants, surgical castration led to long-term graft acceptance and restoration of thymus cells, the team found.
大多数患者在开始去势治疗后一到两年,癌细胞会随着时间的推移而演变为去势抵抗。
In most patients, cancer cells develop castration resistance over time - on average, between 1 - and two years after the start of treatment.
结果:去势大鼠骨组织皮质及骨小梁变薄,骨矿化率增高,矿化缘长度增加,小梁表面破骨细胞数明显增多。
Results The trabecular bone volume and mean cortical thickness decreased in OVX, however, the number of osteoclast were higher than normal rats.
活性维生素D3组各指标与假手术组,相似,但成骨细胞指数高于假手术组与去势组相似,表明活性维生素D3通过抑制雌激素缺乏状态下过高的骨吸收而达到防止骨丢失的作用。
All the changes of indicators in the vit D3 treated group and the CEE3 treated group were similar to those in the sham-operated group, but their mechanisms acting upon bone metabolism are different.
活性维生素D3组各指标与假手术组,相似,但成骨细胞指数高于假手术组与去势组相似,表明活性维生素D3通过抑制雌激素缺乏状态下过高的骨吸收而达到防止骨丢失的作用。
All the changes of indicators in the vit D3 treated group and the CEE3 treated group were similar to those in the sham-operated group, but their mechanisms acting upon bone metabolism are different.
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