方法：以大鼠多囊卵巢为动物模型，采用电子显微镜及3-末端原位标记法观察了大鼠多囊卵巢颗粒细胞凋亡的情况。
Methods: PCO model of rat was established. Ovaries were fixed and processed for ultrastructural observation. DNA fragments in apoptotic cells were detected by in situ DNA 3 end labeling method.
结论：快速引物原位标记技术可用于鼻咽癌冰冻组织切片中染色体的检测，染色体数目的改变可作为鼻咽癌诊断的重要参考指标。
CONCLUSION: The technique of rapid PRINS could be used to detect chromosomes in frozen section tissues, and the chromosomal abnormalitie s would be helpful in diagnosis of NPC.
目的探讨引物原位标记法（PRINS）结合经腹脐血穿刺，应用于脐血中期细胞快速产前诊断18号染色体数目异常的可行性。
Purpose To study the feasibility of PRINS for rapid prenatal diagnosis of fetal 18 aneuploidy in metaphase cells from umbilical blood.
方法用碱性磷酸酶-抗碱性磷酸酶（APAAP）免疫酶标和DNA末端原位标记（ISEL）双重染色方法检测38例急性白血病诱导化疗前后骨髓涂片中细胞凋亡程度及细胞类型，初治组17例与2 1例经治病例对照。
Methods A double-stained way of APAAP and in situ DNA end labeling (ISEL) were used to detect apoptosis characteristics in 38 cases of acute leukemia, including 17 untreated and 21 treated patients.
方法用碱性磷酸酶-抗碱性磷酸酶（APAAP）免疫酶标和DNA末端原位标记（ISEL）双重染色方法检测38例急性白血病诱导化疗前后骨髓涂片中细胞凋亡程度及细胞类型，初治组17例与2 1例经治病例对照。
Methods A double-stained way of APAAP and in situ DNA end labeling (ISEL) were used to detect apoptosis characteristics in 38 cases of acute leukemia, including 17 untreated and 21 treated patients.
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