事先用氨基酸脱羧酶抑制剂异烟肼处理，或用GABA受体拮抗剂印防己毒素处理，可阻遏安定减低膈神经放电幅度的作用。
Pretreatment of either isoniazid, an aminoacid decarboxylase inhibitor, or GABA receptor antagonist picrotoxin prevented thedepressant effect of diazepam on the amplitude of phrenic discharge.
结论：褪黑素延长小鼠睡眠时间的作用与褪黑素3型受体无关，而与GABAA受体关系密切，其作用主要由印防己毒素结合位点介导。
Conclusion: Melatonin does not exhibit its potentiation sleeping time in mice through melatonin 3 receptor. Hypnotic activity of melatonin may be mediated through picrotoxin site on GABAA receptor.
结论：褪黑素延长小鼠睡眠时间的作用与褪黑素3型受体无关，而与GABAA受体关系密切，其作用主要由印防己毒素结合位点介导。
Conclusion: Melatonin does not exhibit its potentiation sleeping time in mice through melatonin 3 receptor. Hypnotic activity of melatonin may be mediated through picrotoxin site on GABAA receptor.
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