单核细胞趋化蛋白- 1是引起慢性炎症的主要趋化因子并且在心力衰竭的发病学中起着重要作用。
Monocyte chemoattractant protein-1 is the main chemotactic factor for the pathogenesis of chronic inflammation and plays an important role in the pathogenesis of heart failure.
目的探讨同型半胱氨酸(HCY)对内皮细胞中单核细胞趋化蛋白1 (MCP 1)表达的影响。
Objective To investigate the effects of homocysteine (HCY) on the expression of monocyte chemoattractant protein? 1 (MCP? 1) in endothelial cells.
目的制备表达人单核细胞趋化蛋白- 1 (MCP - 1)复制缺陷型重组腺病毒。
Objective To construct replication deficient recombinant adenovirus of human monocyte chemoattractant protein-1 (MCP-1) by homologous recombination.
目的研究单核细胞趋化蛋白-1（MCP- 1）在B3型柯萨奇病毒（CVB3）诱导病毒性心肌炎（VMC）发病中的作用。
Objective To investigate the role of monocyte chemoattractant protein 1(MCP 1) in viral myocarditis (VMC) induced by coxsackievirus Group B Type 3 (CVB3).
目的研究单核细胞趋化蛋白1（MCP1）在B3型柯萨奇病毒（CVB3）诱导病毒性心肌炎（VMC）发病中的作用及其机制。
Purpose To investigate the role of monocyte chemoattractant protein-1(MCP?1) in viral myocarditis (VMC) induced by coxsackievirus group B type 3 (CVB3) and its mechanism in pathogenesis of VMC.
单核细胞趋化蛋白- 1作为重要的促炎因子之一，与心力衰竭的关系十分密切。
Monocyte chemotactic protein-1 is an important pro-inflammatory factor, which has a close link with heart failure.
目的研究晚期糖基化终产物（AGE）修饰蛋白对人内皮细胞分泌单核细胞趋化蛋白1（MCP 1）的影响及其作用的信号传导途径。
Objective To investigate the effects of advanced glycation end products (AGE) on secretion of monocyte chemoattractant protein-1(MCP-1) by human endothelial cells and its signal transduction pathway.
目的研究冠心病合并代谢综合征患者胰岛素抵抗与单核细胞趋化蛋白- 1 (MCP - 1)表达的关系。
Objective To investigate the relationship between insulin resistance and monocyte chemoattractant protein-1 (MCP-1) in patients with coronary heart disease and metabolic syndrome (MS).
目的探讨灯盏花素对糖尿病大鼠肾小管-间质细胞间黏附因子- 1 (ICAM - 1)与单核细胞趋化蛋白- 1 (MCP - 1)表达的影响。
Objective To study the effect of breviscapine on intercellular adhesion molecule-1 (ICAM-1) and monocyte chemotactic protein-1 (MCP-1) expression in tubulointerstitium of experimental diabetic rats.
结果：将编码人单核细胞趋化蛋白—1（MCP—1）基因克隆至融合表达载体pGEX—2T中，DNA测序证实正确。
Results: A gene fragement encoding MCP-1 was cloned into the fusional expression vector PGEX-2T. DNA sequencing indicated that it was correct.
目的研究反义单核细胞趋化蛋白1 (MCP - 1)对系膜细胞MCP - 1分泌及增生的影响。
Objective To examine the influence of antisense MCP-1 on MCP-1 production and mesangial cell proliferation.
目的评价巨噬细胞调理液(MCM)对视网膜色素上皮(RPE)细胞合成单核细胞趋化蛋白-1 (MCP - 1)的作用。
AIM To examine the effects of cultured macrophage conditioned media (MCM) on production and gene expression of monocyte chemotactic protein 1 (MCP 1) of human retinal pigment epithelial (HRPE) cell.
对单核细胞趋化蛋白-1进行干预可能成为未来新的治疗方向。
Therapies confronting monocyte chemoattractant protein-1 may be future new directions.
目的观察高脂血症肾损害大鼠肾组织中骨调素（OPN）和单核细胞趋化蛋白1 （MCP-1）表达变化及辛伐他汀对其表达的影响。
Objective To investigate the expression of osteopontin (OPN) and monocyte chemoattractant protein 1(MCP-1)and the effect of simvastatin on them in diet-hypercholesterolemia rats.
目的观察高脂血症肾损害大鼠肾组织中骨调素（OPN）和单核细胞趋化蛋白1 （MCP-1）表达变化及辛伐他汀对其表达的影响。
Objective To investigate the expression of osteopontin (OPN) and monocyte chemoattractant protein 1(MCP-1)and the effect of simvastatin on them in diet-hypercholesterolemia rats.
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