方法：采用单侧输尿管梗阻（UUO）诱导大鼠肾小管间质纤维化模型。
Method:Tubulointerstitial fibrosis model was established by unilateral ureteral obstruction(UUO) rat.
目的：研究肾炎康复片对单侧输尿管梗阻(uuo)大鼠肾间质纤维化的保护作用。
Objective To study the protective effects of Shenyankangfu tablet on renal interstitial fibrosis in rats with unilateral ureteral obstruction (UUO).
方法采用左侧输尿管结扎的方法建立单侧输尿管梗阻（UUO）雄性CD-1小鼠动物模型。
Methods The animal model of renal disease was induced by unilateral ureteral obstruction (UUO) in CD-1 mice.
目的探讨雌激素在单侧输尿管梗阻（UUO）大鼠肾间质纤维化模型中对肾小管上皮细胞表型转化的影响。
To evaluate the effect of estrogen on tubular epithelial cell phenotype transdifferentiation of tubulointerstitial fibrosis in unilateral ureteral obstruction(UUO)rats.
目的：动态观察P 21在单侧输尿管梗阻肾间质纤维化大鼠模型中的表达，以及依那普利对其表达的调节。
Objective To investigate the expression of P21 in renal interstitial fibrosis rats and the effect of enalapril on it.
目的证实结扎致单侧输尿管梗阻(uuo)大鼠模型梗阻侧肾脏是否存在低氧，不同时间点低氧的特点及低氧与肾间质纤维化的关系。
Purpose To observe whether hypoxia exists in the obstructed kidney of unilateral ureteral obstruction (UUO) rat model and its distribution relationship with tubulointerstitial fibrosis.
单侧输尿管梗阻组（U）：大鼠行手术剖腹，分离并于肾盂下结扎左侧输尿管，同时术前一天开始每日给以安慰剂生理盐水灌胃处理；
UUO group rats received an operation with left ureteral obstruction below the renal pelvis and were also gavaged with saline daily;
例如，ED5可以减少小鼠尿路梗阻（单侧输尿管结扎）或通过电穿孔法切除肾脏7天后皮质早期生长反应基因-1信使RNA表达和间质纤维化。
For example, ED5 reduces cortical Egr-1 mRNA expression and interstitial fibrosis in rats 7 days after renal obstruction (unilateral ureteral ligation) and delivery by electroporation.
例如，ED5可以减少小鼠尿路梗阻（单侧输尿管结扎）或通过电穿孔法切除肾脏7天后皮质早期生长反应基因-1信使RNA表达和间质纤维化。
For example, ED5 reduces cortical Egr-1 mRNA expression and interstitial fibrosis in rats 7 days after renal obstruction (unilateral ureteral ligation) and delivery by electroporation.
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