应用酶联免疫法分析半抗原抗体滴度。
The titers were determined by enzyme linked immunosorbent assay.
磺胺嘧啶的分子量为250，为半抗原。
在有了目标之后，再将一系列叫做半抗原的小分子附属在载体上。
Then there is the target itself, a set of smaller molecules called haptens that are attached to the carrier.
磺胺二甲基嘧啶半抗原是一种化合物，其结构为式i所示。
The sulfamethazine hapten is a compound and the structural formula is shown as formula I.
本发明制备方法简便可行、成本较低，半抗原产率较高。
The preparation method in the invention features convenience and feasibility, lower cost and higher yield of hapten.
目的：探讨用半抗原修饰的瘤苗治疗小鼠t淋巴细胞瘤的方法。
Aim: To study the method for treating mouse t lymphoma with hapten modified tumor vaccine.
本发明公开了一种三聚氰胺半抗原、抗原及其制备方法和应用。
The invention discloses a melamine hapten, a melamine antigen and a preparation method and applications thereof.
他们利用电脑模型来展现三维半抗原并解决了分子重新排布的问题。
They used computer models to visualise the haptens in three dimensions and thus work out how the molecules could be rearranged such that they could not spring.
这些检测方法在检测血清中的靶向半抗原表现出了足够高的灵敏度。
RESULTS: The developed assays exhibited sensitivity high enough to detect target haptens in serum samples.
本发明公开了一种呋喃唑酮代谢物半抗原、抗原及其制备方法和应用。
The invention discloses furazolidone metabolite hapten and antigen as well as a preparation method and application thereof.
然后是与载体结合的靶物质本身，他们是一组叫做半抗原的较小的分子。
Then there is the target itself, a set of smaller molecules called haptens that are attached to the carrier.
半抗原和牛血清白蛋白及卵清蛋白的结合比分别是21：1和11：1。
Ratios of hapten intergraded with BSA and OVA were 21:1 and11:1, respectively.
本发明公开了硝基呋喃类物质的一种半抗原、抗原及其制备方法与应用。
The invention discloses hapten and antigen of nitrofurans and a preparation method and application thereof.
本发明公开了一种氰脲三酰胺半抗原、人工抗原和抗体制备方法及应用。
The invention discloses a method for preparing cyanide-urea triamide hapten, artificial antigen and antibody as well as application thereof.
最后，有一种叫做佐药的鸡尾酒帮助免疫系统对载体蛋白和半抗原做出反应。
Finally, there is a chemical cocktail called an adjuvant that helps get the immune system to pay attention to the carrier protein and the haptens.
以辣根过氧化物酶采用改良的过碘酸钠法标记抗体、混合酸酐法标记半抗原。
The horseradish peroxidase (HRP) tagged antibody was prepared by means of modified NaIO 4 method and the HRP tagged hapten was prepared by means of mixed anhydride method.
最后，一个叫做辅助剂的化学品混合体可以帮助免疫系统注意到蛋白质载体和这些半抗原。
Finally, there is a chemical cocktail called an adjuvant that helps get the immune system to pay attention to the carrier protein and the haptens.
最近引进的采用双官能抗体和小分子的半抗原的两步法在一定程度上满足了这个要求。
A recently introduced approach satisfies this requirement to some extent: the use of low molecular weight haptens with bifunctional antibodies.
鉴定结果表明：人工抗原的紫外光谱图与载体蛋白和半抗原的紫外光谱相比均发生变化；
The results showed that UV absorbance spectrum of artificial antigen of GA-BSA changed compared with carrier BSA and hapten GA.
方法：提出“潜过渡态”半抗原设计策略，并据此设计、合成了新型半抗原和人工抗原。
Methods: a new hapten design strategy termed "pro transition state" hapten strategy was proposed and a novel hapten and relative synthesized antigens were designed and synthesized.
利用组合库和噬菌体展示技术，我们证明半抗原特异性抗体确实存在有外围载体的某些遗迹。
By using combinatorial library and phage display technologies on a hapten-specific antibody we were able to demonstrate that a peripheral carrier imprint indeed exists.
上述观察结果为阐明自体抗原的半抗原化为何会引起自身免疫性疾病提供了一种似乎合理的解释。
The observed results provide a plausible mechanism for how haptenization of self-antigens can lead to the development of autoimmunity.
修饰的乙肝核心蛋白或其聚集的核衣壳蛋白颗粒可悬垂连接到半抗原上以形成一修饰的核衣壳偶联物。
The modified hepatitis B core protein or its aggregated nucleocapsid protein particles can be pendently linked to a hapten to form a modified nucleocapsid conjugate.
然后通过碳二亚胺法将半抗原与载体蛋白偶联制备人工抗原，采用紫外扫描及SDS - PAGE鉴定。
Then, antigen was prepared by conjugation of hapten with carrier protein by carbodiimide (EDPC) method and was identified by UV spectroscopy and SDS-PAGE.
在半抗原成形后，他们将这些新的半抗原分子附到蛋白质载体上并与辅助剂混合再注射到小鼠身上等待结果。
Once built, they attached the new hapten molecules to carrier proteins, mixed them with adjuvant, injected the results into mice and waited.
结果显示，质谱测定己烯雌酚半琥珀酸的分子量为368：每个BSA分子结合了约32个己烯雌酚 半抗原；
The result shows: The molecular mass of DES is 368; And there are 32 DES Hapten binded with each BSA;
农药分子半抗原的合成直接影响后期制备抗体的质量，对于建立农药分子特异、灵敏的免疫分析方法具有关键性作用。
The synthesis on haptens of pesticides directly influences the quality of the antibodies, and are critical in the format of particular and sensitive immunology assay.
本发明提供了一种新尼古丁衍生物形式的半抗原，所述半抗原可适当地与合适的载体缀合以得到针对尼古丁成瘾的有效疫苗。
The present invention provides a hapten in the form of a novel nicotine derivative that may suitably be conjugated with an appropriate carrier to yield an effective vaccine against nicotine addiction.
过敏性疾病是指机体通过吸入、食入、注入或接触某种抗原物质或半抗原物质后引起各种各样的功能障碍或组织损伤的一类疾病。
Anaphylactic disease is a kind of disease with kinds of dysfunction or tissue injury resulting from some materials of antigen and semiantigen by inspiration, ingestion, injection or contact.
过敏性疾病是指机体通过吸入、食入、注入或接触某种抗原物质或半抗原物质后引起各种各样的功能障碍或组织损伤的一类疾病。
Anaphylactic disease is a kind of disease with kinds of dysfunction or tissue injury resulting from some materials of antigen and semiantigen by inspiration, ingestion, injection or contact.
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