热疗可导致化疗耐药的产生。
结论这些基因表达差异与卵巢癌化疗耐药有关。
Conclusion These genes related to the mechnisms of drug-resistance of ovarian cancer.
目的研究血清细胞角蛋白18 (CK18)水平与非小细胞肺癌患者紫杉醇化疗耐药的关系。
Objective to investigate the relationship between serum cytokeratin 18 (CK18) levels and resistance to paclitaxel chemotherapy in patients with non-small cell lung cancer.
结论肺腺癌细胞的化疗耐药性与放射敏感性之间有一定的内在联系，化疗耐药性导致放疗敏感性降低。
ConclusionThere exists internal relations between the chemoresistance and radiosensitivity of lung adenocarcinoma cisplatin-resistant cell, chemo-resistance leads to reduced radiosensitivity.
目前多数观点认为肝癌属于化疗耐药性疾病，肝癌细胞产生耐药性是化疗失败及肝癌复发的主要原因之一。
Now the most viewpoints are that hepatoma is a chemical therapy drug resistance disease, one of the important causes of failed therapy and relapsed cancer is the hepatocyte's drug resisitence.
假如一些这样的专门化的细胞逃避了化疗或放疗的毁灭，肿瘤能很快的复发，经常是以化疗耐药形式出现。
If some of these specialized cells escaped destruction by chemotherapy or radiation, the tumor would be able to recur quickly, often in a form resistant to chemotherapy.
尽管SCLC化疗的有效率较高，但对于广泛期sclc患者，从化疗耐药开始至患者死亡的中位时间仍不满意。
In spite of the high response rate, the median time from drug-resistance to death of extensive SCLC is still disappointed.
结论HCC化疗多药耐药与其LRP表达有关，LRP表达也与HCC的分化程度有关，检测LRP表达对预测化疗耐药具有指导意义。
Conclusions MDR of HCC is related to LRP expression, LRP gene expression correlates with differential degree of HCC. Detection of LRP expression could predict chemotherapy resistance of HCC.
结论MDR1可能参与胰腺癌细胞株化疗耐药；中等剂量的维拉·帕米联合化疗可逆转具有MDR1表型的人胰腺癌细胞株对adm和MMC的耐药现象。
Conclusions Moderate dose of verapamil can reverse chemoresistance of pancreatic carcinoma cell line to ADM and MMC that might be related to MDR1.
坚决不提倡大规模的预防性化疗，因为对霍乱的传播没有影响，可通过加强抗生素耐药性产生不良作用，并提供了虚假的安全感。
Mass chemoprophylaxis is strongly discouraged, as it has no effect on the spread of cholera, can have adverse effects by increasing antimicrobial resistance and provides a false sense of security.
在出现青蒿素耐药性的地区，观察到的高治愈率主要依赖于联合化疗中非青蒿素成分的疗效。
In artemisinin-resistant areas, the high cure rates observed depend heavily on the efficacy of the non-artemisinin component of the combination.
耐药性产生的起因是对药物敏感的结核病患者进行化疗时，不恰当地使用了抗菌素。
Drug resistance arises due to the improper use of antibiotics in chemotherapy of drug-susceptible TB patients.
但是很显然，如果青蒿素成分的疗效继续降低，对联合化疗中所用非青蒿素药物出现耐药性的风险会加大。
However, it is clear that if the efficacy of artemisinin component continues to decline, there is an increased risk that resistance to non-artemisinin medicines used in the combination will emerge.
世卫组织还正致力于调整直接督导下的短程化疗以便迎接多药物耐药性结核和结核与艾滋病毒合并感染的特殊挑战。
WHO is also working to adapt DOTS to meet the special challenges of multi-drug resistant TB and co-infection with TB and HIV.
虽然药物敏感结核病可以在6个月内治愈，耐药类型的结核病（如：耐多药结核病）需要进行长达两年的全面化疗（使用具有更多副作用的药品）。
While drug-susceptible TB can be cured within six months, forms of drug-resistant TB (such as MDR-TB) require extensive chemotherapy (with drugs which have more side effects) for up to two years.
目的研究长春酰胺、阿克拉霉素、丝裂霉素联合化疗治疗耐药卵巢癌的疗效和毒性反应。
To study the response rate and toxic side effects of vindesine, aclarubicin and mitomycin(VAM) as a new regimen of second line chemotherapy for ovarian carcinoma.
这种方法能够避免标准化疗中两个主要的缺点：一般的治疗手段缺乏针对性和癌症细胞会有耐药性。
The method is intended to sidestep two major drawbacks of standard chemotherapy: the treatment's lack of specificity and the fact that cancer cells often develop resistance.
目的评价国产多西他赛联合奥沙利铂作为铂类耐药的晚期卵巢上皮癌解救化疗的疗效和毒性。
Objective To evaluate the efficacy and toxicity of docetaxel plus oxaliplatin in the treatment of platinum resistance advanced epithelia ovary cancer.
一旦卵巢癌对多种化疗药物产生耐药，则治疗的选择余地较少，而随后治疗的关键在于延长患者的生存期。
Once ovarian cancer becomes resistant to multiple types of chemotherapy, fewer treatment options exist and the focus becomes lengthening patients' survival periods.
她对化疗有极强的耐药性，我们希望她的痛苦能缓解。
She's tolerated the chemotherapy extremely well and we hope she's going into remission.
结论草酸铂为主的化疗对铂耐药或铂敏感的复发卵巢癌均有一定的疗效；
Conclusion oxaliplatin-based chemotherapy is effective both for platinum - sensitive and platinum-resistant recurrent EOC.
目的：探讨乳腺癌新辅助化疗对耐药基因mdr1和MRP表达的影响。
AIM: To investigate the expression of drug resistance genes, MDR1 and MRP, in patients with primary breast cancer after neoadjuvant chemotherapy.
结核病疫情日益严重，尤其是耐药结核分枝杆菌的出现，使抗结核化疗药物面临严峻的挑战。
The epidemic situation of tuberculosis is more and more severe, especially drug-resistant mycobacterium tuberculosis make antituberculous chemical drug facing grim challenge.
目的探讨人肺癌细胞株对化疗药物的敏感性与多药耐药相关基因和凋亡调控基因表达的关系。
Objective To explore the relationship of chemotherapy sensitivity and expression of multidrug resistance genes and apoptosis regulation genes in human lung cancer cell lines.
背景与目的：多药耐药在膀胱癌化疗失败中起着重要作用，关于其机制还不是十分清楚。
BACKGROUND & OBJECTIVE: Multidrug resistance plays an important role in chemotherapy failure of bladder cancer, but its mechanism is unclear.
表皮生长因子受体（EGFR）及其配体的过表达与疾病的迅速进展和对化疗的耐药有密切的联系。
The overexpression of the epidermal growth factor receptor and its ligands correlates with rapidly progressive disease and resistance to chemotherapy.
那些认为会导致对化疗药敏感和耐药的基因与实际的体外化疗敏感性有很大的相关程度。
Cancer found good correlation between genes believed to be involved in drug sensitivity and resistance and actual in vitro chemosensitivity.
化疗仍然是治疗的主要手段，但对正常细胞的毒性和肿瘤细胞耐药影响了治疗效果。
Chemotherapy is still major method, but toxicity to normal cells and resistance to multidrugs influence therapeutic effect.
目的多药耐药性是导致急性白血病化疗失败的主要原因。
Objective Multidrug resistance can eventually result in the chemotherapy failure of acute leukemia.
目的多药耐药性是导致急性白血病化疗失败的主要原因。
Objective Multidrug resistance can eventually result in the chemotherapy failure of acute leukemia.
应用推荐