本文研究了反相高效液相色谱和超速冷冻离心测定雷公藤甲素聚乳酸纳米粒包封率和载药量的方法。
The encapsulation efficiency and drug loading of triptolide-loaded poly (d, L-lactic acid) nanoparticles were analyzed by RP-HPLC and ultracentrifuge method in this study.
结论：本实验制备的HCPT -SSLN包封率和载药量较高，粒径分布均匀，稳定性良好。初步表明HCPT适合进行SSLN包裹。
Conclusion: The HCPT-SSLN has high entrapment efficiency and drug loading, uniform particle size, good stability, which initially indicates that HCPT is fit for being incorporated into SSLN.
结果表明，所得微球粒径适合，分布均匀，性质稳定，载药量和包封率均比较适宜。
The results showed that the particle size and distribution was suitable, quality was stable, drug-loaded and entrapment rate were fine.
方法采用薄膜分散法和冻干工艺进行木犀草素脂质体制备，并以载药量、包封率为评价指标，优化制备处方和工艺。
Optimization of preparation and formulation was accomplished by evaluating the drug-loading amounts and the entrapment efficiency of luteolin liposomes.
本发明制备工艺简单，所 得纳米粒子粒径均匀，粒度分布较窄，对疏水性药物有较高的载药量和包封率。
The invention has simple process, uniform grain diameter, narrow graininess distribution, high carrier and packing rate on hydrophobic drug.
当取代度和相对分子质量相同时，随着投料比的增加，载药量增加而包封率降低。
Higher feed ratio could lead to higher loading capacity and lower encapsulation efficiency under the same degree of substitution of cholesteryl moiety and molecular weights of parent pullulan.
吸水度高的微球载药量和包封率较吸水度低的微球高。
Compared to microspheres with low water absorbing rate, the high batches had higher drug-loading rate and entrapment rate.
吸水度高的微球载药量和包封率较吸水度低的微球高。
Compared to microspheres with low water absorbing rate, the high batches had higher drug-loading rate and entrapment rate.
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