目的:建立小型猪颈动脉粥样硬化性狭窄模型。
Objective: To establish carotid artery atherosclerotic stenosis model in mini-swine.
目的:观察家兔颈动脉粥样硬化模型颈动脉内膜剥脱术(CEA)后早期再狭窄随时间的变化过程,为临床预防再狭窄提供依据。
Objective: to observe the time course of early restenosis of rabbit carotid atherosclerosis model after CEA and to provide information for clinical preventing restenosis.
方法以新西兰兔颈动脉粥样硬化性狭窄动物模型为基础,采用免疫组织化学的方法检测颈动脉内膜切除术后不同时间点新内膜中ICAM - 1、MMP - 2基因的表达。
Methods Using New Zealand Rabbits, carotid atherosclerotic stenosis (CASS) model were created. The expression of ICAM-1 and MMP-2 of neointima after CEA were detected by immunohistochemical technique.
方法以新西兰兔颈动脉粥样硬化性狭窄动物模型为基础,采用免疫组织化学的方法检测颈动脉内膜切除术后不同时间点新内膜中ICAM - 1、MMP - 2基因的表达。
Methods Using New Zealand Rabbits, carotid atherosclerotic stenosis (CASS) model were created. The expression of ICAM-1 and MMP-2 of neointima after CEA were detected by immunohistochemical technique.
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