对近年来血管性痴呆动物模型的造模方法进行了介绍,分析了各种方法的优缺点。
The paper introduced the methods of building model on animal model of vascular dementia in recent years, and analysed the good points and bad points of these methods.
目的建立拟血管性痴呆的动物模型,探讨针刺对VD大鼠模型的学习记忆行为、脑内NO含量、NOS活性及VD大鼠血液流变学的影响。
Purpose To make the rats model of VD and to study the effect of acupuncture on Hemorheology and activity of NOS and content of NO in brains of VD rats.
在研究中应当加强基因芯片技术的应用、设计多种“痴呆”动物模型、借鉴血清药效学的研究方法、重视整体调衡基因的效应和环境等因素的影响。
In the study, attention should be paid to the application of the gene array technique. Animal models of dementia should be designed, research methods used in serum...
这些化合物将会在有痴呆的基因鼠模型中进一步验证,来判断在动物模型中是否也存在类似的阻断效应。
These compounds will be tested in mice that have been genetically modified to have the characteristics of dementia to see if the compounds have similar inhibiting effects in an animal model.
目的建立血管性痴呆(VD)的动物模型,并探讨血管性痴呆认知障碍的发病机制。
Objective To establish an animal model of vascular dementia(VD) in aging rat and study the mechanism of hypomnesis in vascular dementia.
方法:首先建立痴呆动物模型并用脑肽精治疗。
Methods: First of all, the model of dementia mice was established, and the dementia mice were cured with BPC.
目的建立拟血管性痴呆的动物模型,探讨针刺对VD大鼠模型的学习记忆行为及脑内谷胱甘肽过氧化物酶(GSH-PX)及一氧化氮(NO)含量的影响,观察海马神经元细胞凋亡情况。
Purpose To study the effect of acupuncture on the learning dysmnesia of VD rats activity of GSH-PX and content of NO and to observe injured neuron in hippocampal region.
本实验以颅外安置小磁铁吸附经舌下静脉注入四氧化三铁粉的方法建立了一种脑缺血所致血管性痴呆的大鼠动物模型。
The vascular dementia model in rats was reproduced by injecting Fe particles into the sublingual vein, after fixing a magnet on the skull surface.
结论TS G可明显改善模型动物胆碱能系统的损伤,对于老年性痴呆的治疗有重要意义。
CONCLUSION TSG significantly improved the cholinergic damage in model rats, and it may play an important role in Alzheimer's disease therapy.
结论TS G可明显改善模型动物胆碱能系统的损伤,对于老年性痴呆的治疗有重要意义。
CONCLUSION TSG significantly improved the cholinergic damage in model rats, and it may play an important role in Alzheimer's disease therapy.
应用推荐