本化疗方案的剂量限制毒性为骨髓抑制,其中72 %的病人发生3~4度中性粒细胞下降。
The dose limiting toxicity ssociated with this regimen was myelo suppression with grade 3~4 neutrocytopenia in 72 % of patients.
其剂量限制毒性(DLT)为中性粒细胞减少和腹泻,肝肾功能下降会降低最大耐受剂量(MTD)。
The dose limiting toxicity (DLT) of it was neutropenia and diarrhea. Its maximum tolerance dose (MTD) may be reduced by elevated liver or kidney function.
其剂量限制毒性(DLT)为中性粒细胞减少和腹泻,肝肾功能下降会降低最大耐受剂量(MTD)。
The dose limiting toxicity (DLT) of it was neutropenia and diarrhea. Its maximum tolerance dose (MTD) may be reduced by elevated liver or kidney function.
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