目的研究利多卡因凝胶的经皮吸收动力学以及药效学。
Aim To study the cutaneous permeation kinetics and pharmacodynamics of lidocaine gel.
目的：采用高效液相色谱法测定林可霉素利多卡因凝胶中盐酸利多卡因的含量。
OBJECTIVE To determine the content of lidocaine hydrochloride in lincomycin hydrochloride and lidocaine hydrochloride gel by HPLC.
目的：考察多种渗透促进剂对盐酸利多卡因凝胶经皮渗透的影响，并从中筛选其最佳处方组成。
Objective: to study the influence of several different permeation enhancers on transdermal permeation of lidocaine hydrochloride gel to obtain an optimal prescription.
目的：考察多种渗透促进剂对盐酸利多卡因凝胶经皮渗透的影响，并从中筛选其最佳处方组成。
Objectives: Study the influence of several different permeation enhancers on transcutaneous permeation of lidocaine hydrochloride gel to obtain an optimal formula.
目的：制备利多卡因脂质体凝胶，并建立其质量控制方法。
OBJECTIVE: to prepare lidocaine liposome gel and to establish its quality control method.
方法通过均匀实验设计优化利多卡因脂质体的处方和制备工艺，以逆相蒸发-超声法制备LDH脂质体，再用卡波普为基质制成凝胶剂；
The LDH liposome was prepared by the reverse-phase evaporation and ultrasound method, the carbopol was added as a support base for the preparation of the liposomeal gel.
方法通过均匀实验设计优化利多卡因脂质体的处方和制备工艺，以逆相蒸发-超声法制备LDH脂质体，再用卡波普为基质制成凝胶剂；
The LDH liposome was prepared by the reverse-phase evaporation and ultrasound method, the carbopol was added as a support base for the preparation of the liposomeal gel.
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