目的探讨凝血酶对体外培养的原代大鼠脑微血管内皮细胞(bmvec)的损伤作用及凝血酶抑制剂水蛭素的保护作用。
AIM to investigate the apoptotic effect of thrombin on brain microvascular endothelial cell (BMVEC) of cultured rat, and the protective effect of hirudin, an inhibitor of thrombin.
目的研究携带血管抑素K1-5基因的腺病毒载体对其对血管内皮细胞增殖的抑制作用。
Objective To investigate the suppression effects of a adenovirus vector containing angiostatin K1-5 gene to the proliferation and migration of vascular endothelial cells.
采用划线法和MTT法观察血管生成抑制素和反应停对淋巴管内皮细胞增殖和游走的影响。
Scraping line method and MTT were used to observe the effect of angiostatin and thalidomide on proliferation and migration of LEC.
结论葛根素可以缓解培养人脐静脉内皮细胞内钙超载,其作用机制可能与拮抗膜上电压依赖型钙通道和抑制内质网钙库释放有关。
Conclusion the mechanism of puerarin reducing the overload of calcium in HUVECs may be related with blocking both voltage-dependent calcium channels and the release of calcium pool in endoplasm.
内皮抑素是一种抗血管生成的抑制因子,它特异性地作用于新生微血管的内皮细胞,其水平与肿瘤血管生成有着明显的相关性。
Endostatin is a kind of angiogenesis inhibitor, specific effecting in the new microvascular endothelial cells. The level of endostatin and the angiogenesis of tumor have a close correlation.
从内皮细胞生长抑制素的来源、结构、药理作用、作用机制、制备方法、应用研究等诸方面,综述其最新研究进展。
The current progress in research on endostatin, including its source, structure, pharmacological action, mechanism of action, preparation method, application research and so on, was summarized.
从内皮细胞生长抑制素的来源、结构、药理作用、作用机制、制备方法、应用研究等诸方面,综述其最新研究进展。
The current progress in research on endostatin, including its source, structure, pharmacological action, mechanism of action, preparation method, application research and so on, was summarized.
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