目的探讨共刺激分子在哮喘发病免疫学机制中的作用。
Objective to investigate the potential role of co-stimulators in the immunological mechanism of asthma.
已有研究表明，共刺激分子的表达与同种异体移植排斥反应有关。
It has been showed that the expressions of costimulatory molecules are associated with xero organ transplantation rejection.
可见，肿瘤细胞上共刺激分子缺陷是肿瘤免疫逃逸的重要机制之一。
Therefore, deficiency of costimulatory molecules on tumor cells is one of the important mechanisms of tumor immune escape.
结论：共刺激分子CD 154和ICOS的全血基因表达量能可靠的区分排异患者和对照患者。
CONCLUSIONS: The whole blood gene expression quantities of costimulatory molecules CD154 and ICOS reasonably robustly differentiated rejection patients from control patients.
目的探讨可诱导共刺激分子(ICOS)在系统性红斑狼疮(SLE)患者外周血t淋巴细胞的表达。
Objective to investigate the expression of inducible co-stimulator (ICOS) on t lymphocytes in peripheral blood from the patients with systemic lupus erythematosus (SLE).
目的探讨共刺激分子B7 1 (CD80)在血液系统恶性肿瘤发病学及免疫基因治疗中的重要作用。
Objective to explore the significance of costimulatory molecule B7-1 (CD80) and MHC molecules in the pathogenesis of hematologic malignant tumors and in the immuno-genetic therapy.
单用DNA疫苗或联用TLR免疫的组间的树突状细胞表面上的共刺激分子的表达水平没有统计学上的显著差异。
No statistically significant difference in the expression levels of co-stimulatory molecules on dendritic cells surface between the groups immunized with DNA vaccine alone or with TLRs.
结论：不同强度高压芒刺静电场可引起免疫共刺激分子表达量不同的生物效应，在免疫调节反应中发挥重要功能。
Conclusion The different doses of HVPEF might cause different biological effects, which suggests HVPEF has potential immune-regulatory effects and might play an important role in immune modulation.
结论(1)CAA患者外周血共刺激分子CD 2 8异常高表达，提示CD 2 8失调可能在CAA免疫发病中起重要作用。
Conclusion (1) The abnormal high expression of peripheral blood co stimulatory molecules CD28 suggested CD28 disorder may play an important role in immuno pathogenesis of CAA.
目的：研究银屑病患者外周血T淋巴细胞表面共刺激分子CD80的表达及其与银屑病皮损面积和严重程度指数（PASI）的相关性。
Objective: To measure the expression of co-stimulatory molecule CD80 on peripheral blood T lymphocytes in patients with psoriasis and its correlation with psoriasis area and severity index (PASI).
而CD 80是能够与CD 28分子结合的共刺激分子之一，它与T细胞表面CD 28分子的结合为T细胞有效活化提供第二信号。
CD80 is one of the co-stimulatory molecules binding CD28, which binds CD28 on the surface of t cells to provide second signal for efficient activation of t cells.
近年来，肿瘤坏死因子受体超家族成员-OX40 (CD134)，作为一共刺激分子对于维持CD 4 +T细胞的活化、增值、存活起到关键性作用。
In recent years, tumor necrosis factor receptor (TNFR) family member-OX40 (CD134), as a key co-stimulatory molecule, involved in maintenance of activation, proliferation, survival of CD4 + t cells.
近年来，肿瘤坏死因子受体超家族成员-OX40 (CD134)，作为一共刺激分子对于维持CD 4 +T细胞的活化、增值、存活起到关键性作用。
In recent years, tumor necrosis factor receptor (TNFR) family member-OX40 (CD134), as a key co-stimulatory molecule, involved in maintenance of activation, proliferation, survival of CD4 + t cells.
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