同时，通过处理共刺激信号的方法诱导免疫耐受在异体手移植中具有一定的应用前景。
Meanwhile co-stimulating signal induced immunological tolerance is proved promising for the application of hand transplantation.
角膜移植手术失败的主要原因是T细胞介导的免疫排斥反应，T细胞的充分活化需要共刺激信号的协同作用。
The leading cause of corneal graft failure is T cell-mediated immune rejection. Costimula-tion has been shown to be necessary for full activation of naive T cell.
目的最新实验数据显示了CD 2 8 B7和CD 40 CD 15 4共刺激信号通路在T细胞活化与效应过程中起重要作用。
Objective Recent experimental data indicate that the costimulatory signal pathways of CD28 B7 and CD40 CD154 offer essential roles for t cell activation and effecting.
而CD 80是能够与CD 28分子结合的共刺激分子之一，它与T细胞表面CD 28分子的结合为T细胞有效活化提供第二信号。
CD80 is one of the co-stimulatory molecules binding CD28, which binds CD28 on the surface of t cells to provide second signal for efficient activation of t cells.
CD4 7是T细胞活化的共刺激因子，活化T细胞凋亡过程，诱导T细胞无反应性，加强TCR信号传导的效率；
CD47 induces costimulatory signals on activation of T cell, T cell apoptosis and T cell anergy and enhances the efficiency of TCR signaling;
CD4 7是T细胞活化的共刺激因子，活化T细胞凋亡过程，诱导T细胞无反应性，加强TCR信号传导的效率；
CD47 induces costimulatory signals on activation of T cell, T cell apoptosis and T cell anergy and enhances the efficiency of TCR signaling;
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