转氨酶水平轻微升高可能反映了甲氨蝶呤对肝脏的早期毒性作用,尽管也可能是全身感染引起的非特异性反应。
The slightly elevated levels of aminotransferases may reflect an early toxic effect of methotrexate on the liver, although a nonspecific response to a systemic infection is also possible.
采用腹腔注射试验观察其全身急性毒性作用。
To investigate it's systemic acute toxicity by peritoneal injection.
制备领下腺脱细胞基质支架材料的浸提液,通过急性全身毒性试验,分析脱细胞后的生物衍生支架材料对机体的毒性作用。
The extracting liquid of submandibular gland acellular matrix scaffold material was made, and its toxicity effect to the body was analyzed by acute systemic toxicity test.
毒性作用通过急性全身毒性试验、细胞毒性试验和皮肤斑贴试验检测。
Toxicity testing is checked by acute general toxicity, in vitro cytotoxicity and sticking on skin assay.
结论:CHIP腹腔ddp浓度高,血浆峰值较低,以及高温作用,有利于化疗药物在局部对肿瘤细胞发挥作用,减少肾毒性和全身副作用。
Conclusion: CHIP provides high concentration of DDP in the peritoneal cavity, inducing higher local tumoricidal effect, lower nephric and systemic toxicity.
结论:适当浓度的亚砷酸可引起神经轴突的损害,且对全身及周围软硬组织无毒性破坏作用。
Conclusion: Suitable arsenic trioxide concentration can damage nerve axons permanently, and can not bring side effect to the structure around the nerve and whole body.
结论:适当浓度的亚砷酸可引起神经轴突的损害,且对全身及周围软硬组织无毒性破坏作用。
Conclusion: Suitable arsenic trioxide concentration can damage nerve axons permanently, and can not bring side effect to the structure around the nerve and whole body.
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