背景：人胚胎干细胞传代培养的关键是抑制其自发分化、保证细胞的全能性。
BACKGROUND: Key point for subculture of human embryonic stem cells is to inhibit spontaneous differentiation and make sure totipotency of cells.
胚胎干细胞是来源于附植前胚胎的内细胞团或附植后胎儿的原始生殖细胞具有发育全能性的细胞。
Embryonic stem cell is a kind of undifferentiated pluripotent stem cell, which stems from pr Eimplantation ICM or early fetus primordial germ cell.
脂肪干细胞是已知的多能干细胞，它们能产生多种细胞、组织类型，但是他们不如胚胎干细胞全能性。
The stem cells found in fat are known as multipotent stem cells. They can produce a variety of cell and tissue types, but are not as flexible as embryonic stem cells.
目的：人胚胎干细胞传代培养的关键是抑制其自发分化、保证细胞的全能性。
AIM: the key of the human embryonic stem cell culture is to guarantee the totipotency and inhibit spontaneous differentiation.
对于干细胞来说，时间是关键。为了维持分化的全能性，需要一种分子机制，将细胞维持在自我更新的状态直到这些干细胞被邻近组织需要。
For stem cells, timing is key: To maintain their versatility they rely on a molecular mechanism that keeps the cells in a state of self-renewal until they are needed by adjacent tissue.
端粒长度的维持以及端粒结构的稳定在细胞衰老、癌症发生以及干细胞全能性自我更新能力维持等生命过程中都起重要作用。
The maintenance of telomere length and structure plays important roles in many biological processes including cellular aging, tumor genesis and stem cell self-renewal.
端粒长度的维持以及端粒结构的稳定在细胞衰老、癌症发生以及干细胞全能性自我更新能力维持等生命过程中都起重要作用。
The maintenance of telomere length and structure plays important roles in many biological processes including cellular aging, tumor genesis and stem cell self-renewal.
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