目的:探讨消减免疫法在分析肝癌细胞凋亡反应中瞬时表达的某些相关抗原分子的作用。
Aim: to explore the role of subtractive immunization techniques in analysis of some transiently expressed antigens of hepatoma apoptotic cells during apoptotic response.
黑色素瘤抗独特型抗体疫苗能模拟肿瘤相关抗原,激发机体的抗肿瘤免疫应答,已在许多动物实验和临床试验中得到证实。
It has been demonstrated that anti-idiotypic antibody vaccines against melanoma can mimic tumor-associated antigens and activate anti-tumor immune responses in many animal models and clinical trials.
方法:用APAAP免疫酶标法检测10例经il - 2激活的急性白血病患者骨髓细胞相关抗原标记及活化过程中的变化。
Methods: 10 patients with acute leukemia were selected and their bone marrow cell related antigen labeling and activation process changes activated by IL-2 were detected by APAAP method.
消减免疫法有助于制备抗在凋亡细胞高表达,而在非凋亡细胞低表达或不表达的凋亡相关抗原的抗体。
Subtractive immunization is helpful for preparing the antibodies against the apoptosis-associated antigens which expresses highly in apoptotic cells, but lowly or barely in non-apoptotic cells.
目的探讨MAGE-1基因编码的肿瘤相关抗原作为肝细胞性肝癌(HCC)主动免疫治疗攻击靶点的可能性。
Objective To explore the possibility of tumor associated antigen encoded by MAGE-1gene used as a tarest for immunotherapy in HCC patients.
方法:采用脐带血来源的单核细胞制备树突状细胞,体外经s- 180细胞肿瘤相关抗原(TAA)致敏后免疫小鼠,一周后接种s - 180细胞株。
Methods: DCs were derived from cord blood monocytes, then were pulsed by tumor associated antigen (TAA) extracted from human stomach cancer S-180 cell line.
作为一种自身免疫性疾病,类风湿性关节炎的发病与异常的抗原抗体反应息息相关。
As an autoimmune disease, rheumatoid arthritis, and the incidence of abnormal antigen-antibody reactions are closely related.
方法:用人结肠癌细胞株lovo免疫小鼠,用间接细胞ELISA和免疫组化的方法筛选抗结肠癌相关抗原的单抗。
Methods: the mice were immunize with LOVO, and the mAb were screened by indirect cell ELISA and immunohistochemistry.
以人疱疹病毒为抗原,用酶免疫法(EIA)比较在不同生境中,红面猴B病毒相关抗体阳性率的差异:野外捕获组阳性率为76.2 % ;
The related antibody to virus(BVRA) of M. arctoides , which were from, the different habitat, was detected by EIA using HSV as antigen. The Positive rate of the wild captive group was 76.2%;
她强调,人类白细胞抗原基因就与免疫功能相关。
她强调,人类白细胞抗原基因就与免疫功能相关。
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