目的评价国产注射用克林霉素磷酸酯的安全性。
Objective To observe the effects of the Clindamycin Phosphate injection and evaluate its safety.
介绍了制备克林霉素磷酸酯中间体丙酮叉的工艺改进方法。
An improved method for synthesis of clindamycin acetonide was introduced.
方法采用高效液相色谱法测定注射用克林霉素磷酸酯的稳定性。
Methods HPLC was used to determine the concentrations and variation of the samples.
目的：建立克林霉素磷酸酯氯化钠注射液细茵内毒素检查的方法。
Objective: to establish the bacterial endotoxin testing method (BET) of Clindamycin Phosphata and Sodium Chloride Injection.
结论：国产克林霉素磷酸酯治疗需氧革兰阳性菌感染疗效好且安全。
CONCLUSION: The domestic clindamycin phosphate has a good efficacy and safety for treatment of infections caused by gram-positive aerobic bacteria.
结论：克林霉素磷酸酯搽剂是一种治疗寻常型痤疮比较安全、有效的外用制剂。
Conclusion: Clindamycin phosphate liniment is a safe and effective topical preparation for treatment of acne vulgaris.
结果注射用克林霉素磷酸酯无过敏反应，无溶血现象，对静脉血管、肌肉无刺激反应。
Results Clindamycin Phosphate injection had no allergy effect and hemolysis phenomenon, it had no significant stimulation effect on vessel and muscles.
目的：探讨克林霉素磷酸酯对恶性肿瘤放疗后继发肺部厌氧菌感染的治疗疗效及不良反应。
Objective: To investigate the therapeutic outcome and effect of Clindamycin Phosphate in the treatment of successive lung infection with anaerobic bacteria after radiotherapy.
方法采用过敏试验、静脉血管刺激试验、肌肉刺激试验、溶血试验观察克林霉素磷酸酯的安全性。
Methods the safety of Clindamycin Phosphate injection was evaluated by the allergy test, venous and muscle stimulation test and hemolysis test.
本发明克林霉素磷酸酯组合药物在安全性、稳定性、疗效都全面优于现有技术制备的克林霉素磷酸酯。
The clindamycin phosphate composite medicine of the invention is fully superior to the clindamycin phosphate prepared by the prior art in the aspects of safety, stability and therapeutic effect.
目的对不同厂家生产的克林霉素磷酸酯注射液的热稳定性进行了研究并对其主要降解产物进行LC - MS鉴定。
OBJECTIVE To investigate the thermal stability of clindamycin phosphate injection of different manufacturers and identify the degradation products by LC-MS.
针对克林霉素磷酸酯工业生产过程中解吸液的组分特性和目前传统生产技术存在的问题，研究了用纳滤膜浓缩替代减压蒸馏浓缩的可行性。
Aimed to solve the problem in the former production process of Clindamycin Phosphate (CLP), the paper discussed the feasibility that the desorption solution of CLP was concentrated by nanofiltration.
针对克林霉素磷酸酯工业生产过程中解吸液的组分特性和目前传统生产技术存在的问题，研究了用纳滤膜浓缩替代减压蒸馏浓缩的可行性。
Aimed to solve the problem in the former production process of Clindamycin Phosphate (CLP), the paper discussed the feasibility that the desorption solution of CLP was concentrated by nanofiltration.
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