目的:探讨冰片对兔角膜上皮细胞促渗透作用的机理。
OBJECTIVE: to investigate the mechanism of osmosis of cytomembrane of corneal epithelium promoted by Borneolum in the rabbits eye.
用改良的扩散装置评价了盐酸尼卡地平(1)通过脱毛大鼠皮肤的渗透动力学以及促渗剂月桂氮酮(2)的作用。
The in vitro permeation kinetics of nicardipine hydrochloride (1) through the depilatory rat skin and the effect of laurocapram (2) using a modified diffusion cell were evaluated.
方法采用小鼠离体皮肤作为渗透屏障,研究不同浓度氮酮对阿糖胞苷促渗作用的影响。
Methods Rats skin in vitro was applied, studying the effect of different concentrations of azone in Cytarabine ointment on drug permeation.
结果与结论:不同浓度的氮酮对复方替硝唑凝胶中3组分的渗透性均有促进作用,其中浓度为2 %的氮酮透皮促渗作用最显著。
RESULTS&CONCLUSION:Azone at different concentrations could promote the permeability of3ingredients of compound tinidazole gel, and2%azone had the most obvious permeation-enhancing effect.
目的利用表面活性剂的促渗作用,提高脂溶性药物通过电致孔形成的水性通道的经皮渗透量。
OBJECTIVE To enhance the transdermal delivery of lipophilic drugs through the local hydrophilic transport regions (LTRs) formed during electroporation by applying surfactant.
目的利用表面活性剂的促渗作用,提高脂溶性药物通过电致孔形成的水性通道的经皮渗透量。
OBJECTIVE To enhance the transdermal delivery of lipophilic drugs through the local hydrophilic transport regions (LTRs) formed during electroporation by applying surfactant.
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