• 同时,还研究了药量PMT影响PMT的体外药物释放行为

    At the same time, the influences of the drug-fed amount on PMT and release behavior in vitro of PMT were investigated.

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  • 体外药物释放评价结果表明药物载体具有良好缓释效果显影性。

    The results of drug release in situ showed the materials have good sustained drug release effect.

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  • 目的交联透明质衍生物制备载药水凝胶进行体外药物释放研究。

    OBJECTIVE To evaluate drug release properties in vitro of the hydrogel films made of cross-linked hyaluronic acid derivatives.

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  • 目的以交透明载体制备环孢素眼植入凝胶,观察其体外药物释放特性

    Primary study of characteristics and biocompatibility of the films made of cross-linked hyaluronic acid;

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  • 目的考察阳离子型硬脂嫁接物理化性质及载胶团的体外药物释放

    Aim to prepare the micelles of stearic acid grafted chitosan oligosaccharide and investigate the drug release from micelles.

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  • 结论本法准确可靠,操作简便适用缓释bcnu体外药物释放动力学研究

    Conclusion This high performance liquid chromatography method is simple, sensitive and accurate. It is suitable for released kinetics study of controlled-release microspheres of BCNU loading in vitro.

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  • 体外释放试验中可知大小药物释放很大作用药物开始释放微球大小负相关。

    We show from in vitro release experiments that microsphere size has a significant effect on drug release rate. The initial release rate decreased with an increase in microsphere size.

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  • 药物体外释放渗透受到多种处方因素的调节。

    The drug release and permeation were observed to be dependent on some factors.

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  • 前言:目的:建立一种适用于长效药物体外释放方法

    Objective: To establish a novel release method of sustained-release medications in vitro.

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  • 本文简要介绍了几种控释骨架药物体外释放行为评价方法

    A few of evaluation methods for drug release in vitro of sustained-controlled matrix tablets were introduced in this review.

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  • 结果本文自制硝苯地平缓释微丸亲水性凝胶骨架制剂,体外释放机制包括药物扩散骨架溶蚀两种作用。

    Results the nifedipine sustained-release beads was hydrophilic gel frame, drug diffusion and frame erosion was the release mechanisms in vitro.

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  • 体外考察影响药物释放因素

    The factors on drug release were investigated.

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  • 茶碱模型药物,模拟体外释放结果表明,共聚物胶束对茶碱的体外分为缓慢释放平衡释放三个阶段。

    The vitro release result which used theophylline as model drug showed, the release behavior can divide to sharp release , relaxedly release and equilibrium release periods.

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  • 药物树脂制备体外释放缓释包衣都进行了研究

    The research work was composed of preparation and releasing and coating.

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  • 目的磷酸川芎嗪为模型药物制备脉冲释放考察其体外释放影响因素

    Objective: to prepare tetramethylpyrazine phosphate pulsed-release tablets and subsequently to characterize factors to affect the pulsed release of tetramethylpyrazine phosphate in-vitro.

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  • 结果表明,微球含量51.74%,体外溶出24小时释放30%药物。氟派酸微球金黄色葡萄球菌有明显抑制作用

    The results showed that the microcapsule contained 51.74% of basic drug and only 30% of the drug could be released in 24 hours, Norfloxacin showed significant bacteriostatic effect on s, aureus.

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  • 选用盐酸黄连素模型药物进行包衣片剂体外释放试验。

    Berberine chloride was chosen as model drug to prepare coating tablets.

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  • 结果所研制中药浸膏压敏胶贴片外观均一,黏附性良好残留有机溶剂含量,测试的药物有效成分的体外释放速率高于橡皮膏。

    RESULTS This kind of patch has good surface quality, proper adhesive ability, low-level organic solvents residual volume and higher release speed.

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  • 体外释放研究表明制剂两种药物达到零级释放

    The research of in vitro release indicates that the two drugs of preparation both can reach the zero-order release.

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  • 分别考察了上述因素对于控释片体外释放影响以及药物释放机制

    The factors that control the drug release character of the tablets were investigated. The drug release mechanism of the formulation was also studied.

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  • 对最终体系进行体外药物布洛芬(IBU)的装载释放测试表明,该体系在温度响应控制药物释放方面有着较大的潜在应用前景

    The in vitro test of IBU loading and release illustrated the system had a great potential use for thermo-responsive controlled drug-release.

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  • 首先我们利用特殊的溶剂作为软模板制备得到了磁性温敏微囊,并用作为药物载体抗癌性药物霉素装载体外释放实验做了研究。

    First, the magnetic thermo-sensitive micro-containers were prepared in a novel solvent-templated approach, and the products were used as the carriers to load anti-cancer drug Doxorubicin(DOX).

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  • 测定结果显示,药物体外药量随贴时间延长增加而且持续释放药物12h以上

    The drug releasing in vitro increased as the increase of drug covering time, and lasted for over 12 hours. Thed...

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  • 体外释放第一呈突释效应,而后药物释放基本符合级动力学过程。

    The pattern of drug release for 30 days in vitro fitted to zero order release plot, with an initial burst effect at the first day.

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  • 目的观察体外三氯生抗菌活性水泥时间变化药物释放规律,探讨临床应用价值。

    Objective To observe the rules of Triclosan release from bone cements at different time points and its clinical efficacy against bacteria.

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  • 探讨了前药的体外释药性能,前药系统中性酸性磷酸盐缓冲液中均释放出活性药物分子

    Nanoparticles were well-dispersed with spherical shape, and their surface zeta potentials were slightly positive. The kinetics of hydrolysis for drug delivery system was investigated.

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  • 摘要目的建立一种简便有效药物体外释放度测定方法

    AIM To establish a simple and effective method for assessing the dissolution of Ibuprofen's preparations in vitro.

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  • 摘要目的建立一种简便有效药物体外释放度测定方法

    AIM To establish a simple and effective method for assessing the dissolution of Ibuprofen's preparations in vitro.

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