同时,还研究了投药量对PMT的影响及PMT的体外药物释放行为。
At the same time, the influences of the drug-fed amount on PMT and release behavior in vitro of PMT were investigated.
体外药物释放评价结果表明该药物载体具有良好的缓释效果和显影性。
The results of drug release in situ showed the materials have good sustained drug release effect.
目的对交联透明质酸衍生物制备的载药水凝胶膜进行体外药物释放研究。
OBJECTIVE To evaluate drug release properties in vitro of the hydrogel films made of cross-linked hyaluronic acid derivatives.
目的以交联透明质酸为载体制备环孢素眼植入凝胶膜,观察其体外药物释放特性。
Primary study of characteristics and biocompatibility of the films made of cross-linked hyaluronic acid;
目的考察阳离子型壳寡糖硬脂酸嫁接物胶团的理化性质及载药胶团的体外药物释放。
Aim to prepare the micelles of stearic acid grafted chitosan oligosaccharide and investigate the drug release from micelles.
结论本法准确可靠,操作简便,适用于缓释bcnu微球的体外药物释放动力学研究。
Conclusion This high performance liquid chromatography method is simple, sensitive and accurate. It is suitable for released kinetics study of controlled-release microspheres of BCNU loading in vitro.
从体外释放试验中可知微球大小对药物释放率有很大的作用。药物开始释放率与微球大小负相关。
We show from in vitro release experiments that microsphere size has a significant effect on drug release rate. The initial release rate decreased with an increase in microsphere size.
药物的体外释放和渗透受到多种处方因素的调节。
The drug release and permeation were observed to be dependent on some factors.
前言:目的:建立一种适用于长效药物的体外释放新方法。
Objective: To establish a novel release method of sustained-release medications in vitro.
本文简要介绍了几种缓控释骨架片药物体外释放行为的评价方法。
A few of evaluation methods for drug release in vitro of sustained-controlled matrix tablets were introduced in this review.
结果本文自制硝苯地平缓释微丸为亲水性凝胶骨架制剂,体外释放机制包括药物扩散和骨架溶蚀两种作用。
Results the nifedipine sustained-release beads was hydrophilic gel frame, drug diffusion and frame erosion was the release mechanisms in vitro.
体外考察影响药物释放的因素。
以茶碱为模型药物,模拟体外释放的结果表明,共聚物胶束对茶碱的体外释药可分为突释、缓慢释放、平衡释放三个阶段。
The vitro release result which used theophylline as model drug showed, the release behavior can divide to sharp release , relaxedly release and equilibrium release periods.
对药物树脂的制备、体外释放及缓释包衣都进行了研究。
The research work was composed of preparation and releasing and coating.
目的:以磷酸川芎嗪为模型药物制备了脉冲释放片,并考察其体外释放的影响因素。
Objective: to prepare tetramethylpyrazine phosphate pulsed-release tablets and subsequently to characterize factors to affect the pulsed release of tetramethylpyrazine phosphate in-vitro.
结果表明,微球主药含量51.74%,体外溶出24小时仅释放30%的药物。氟派酸微球对金黄色葡萄球菌有明显抑制作用。
The results showed that the microcapsule contained 51.74% of basic drug and only 30% of the drug could be released in 24 hours, Norfloxacin showed significant bacteriostatic effect on s, aureus.
并选用盐酸黄连素为模型药物进行包衣片剂的体外释放试验。
Berberine chloride was chosen as model drug to prepare coating tablets.
结果所研制的中药浸膏压敏胶贴片外观均一,黏附性良好,残留有机溶剂含量低,测试的药物有效成分的体外释放速率高于橡皮膏。
RESULTS This kind of patch has good surface quality, proper adhesive ability, low-level organic solvents residual volume and higher release speed.
体外释放研究表明制剂中两种药物均可达到零级释放。
The research of in vitro release indicates that the two drugs of preparation both can reach the zero-order release.
分别考察了上述因素对于控释片体外释放度的影响以及药物释放机制。
The factors that control the drug release character of the tablets were investigated. The drug release mechanism of the formulation was also studied.
对最终体系进行的体外药物布洛芬(IBU)的装载和释放测试表明,该体系在温度响应控制药物释放方面有着较大的潜在应用前景。
The in vitro test of IBU loading and release illustrated the system had a great potential use for thermo-responsive controlled drug-release.
首先我们利用一种特殊的溶剂作为软模板制备得到了磁性温敏微囊,并用它作为药物载体对抗癌性药物阿霉素的装载及体外释放实验做了研究。
First, the magnetic thermo-sensitive micro-containers were prepared in a novel solvent-templated approach, and the products were used as the carriers to load anti-cancer drug Doxorubicin(DOX).
测定结果显示,药物体外释药量随贴药时间的延长而增加,而且能持续释放药物12h以上。
The drug releasing in vitro increased as the increase of drug covering time, and lasted for over 12 hours. Thed...
体外释放第一天呈突释效应,而后药物释放基本符合零级动力学过程。
The pattern of drug release for 30 days in vitro fitted to zero order release plot, with an initial burst effect at the first day.
目的观察体外三氯生抗菌活性骨水泥随时间变化的药物释放规律,探讨临床应用价值。
Objective To observe the rules of Triclosan release from bone cements at different time points and its clinical efficacy against bacteria.
探讨了前药的体外释药性能,前药系统在中性和酸性磷酸盐缓冲液中均能释放出活性药物分子。
Nanoparticles were well-dispersed with spherical shape, and their surface zeta potentials were slightly positive. The kinetics of hydrolysis for drug delivery system was investigated.
摘要目的:建立一种简便有效的药物体外释放度测定方法。
AIM To establish a simple and effective method for assessing the dissolution of Ibuprofen's preparations in vitro.
摘要目的:建立一种简便有效的药物体外释放度测定方法。
AIM To establish a simple and effective method for assessing the dissolution of Ibuprofen's preparations in vitro.
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