但是，慢性低氧肺动脉高压大鼠5-HT诱导的血管收缩反应是通过5 - HT _ (2 A)和5 - HT _ (1 B)受体介导的。
However, in hypoxic pulmonary hypertension rats, 5 - HT - induced vasoconstriction is mediated by both the 5 - HT1Band 5 - HT2A receptor.
目的研究中药复方制剂三拗芎葶合剂对实验性低氧性肺动脉高压功能形态学的影响，并初步探讨其作用机制。
Objective To study the effect of San'aoxiongting mixture(SAXTM) on experimental hypoxemia pulmonary arterial hypertension and investigate its mechanism.
目的应用运动心肺负荷试验早期检出慢性阻塞性肺疾病(COPD)运动性低氧血症及运动性肺动脉高压。
Objective Cardiopulmonary exercise test is used for early detection of exercise induced hypoxia and exercise induced pulmonary arterial hypertension of chronic obstructive pulmonary disease (COPD).
结论：高原缺氧诱导了VEGF分泌增多，VEGF在HAPC的肺动脉高压、低氧适应调节及并发症中可能发挥了重要作用。
Conclusion: Hypoxia induces elevated secretion of VEGF and the changes of VEGF may be related to hypoxic pulmonary hypertension, hypoxic adaptative regulation and complications of HAPC.
结论低氧所致CTGF的合成增多在低氧性肺血管重建和肺动脉高压的发病过程中起一定的作用。
Conclusions: the CTGF may play an important role in the pathogenesis process of hypoxic pulmonary vascular remodeling and pulmonary hypertension.
结论：缺氧同时或缺氧后雾化吸入NTG均能选择性地降低急性低氧引起的肺动脉高压，对心肌也有一定的保护作用。
CONCLUSION: NTG nebulization produces a selective pulmonary vasodilation either during or after the exposure of hypoxia and improves myocardial impairment in acute hypoxic newborn piglets.
低氧性肺动脉高压(HPH)是高原适应生理的重要环节，也是各型高原病的发病机理。
Hypoxic pulmonary hypertension (HPH) is a key link of the adaptation physiology in high altitude area and the pathogenesis of all types of high altitude diseases.
方法：低氧性肺动脉高压症患者随机分为两组，28例用肺压平复方治疗，19例用硝苯地平治疗，两组进行观察对比。
Methods: Divide all HPH cases into two groups at random, 28 cases in Feiyanping group and 19 cases inNifedipine group as contrast.
目的：探讨氨溴索对低氧性肺动脉高压大鼠慢性肺损伤的对抗作用。
AIM: To investigate the effect of ambroxol on pulmonary and vascular injury in chronically hypoxic rats.
结论高原低氧环境血清vegf的含量明显升高，可能在低氧性肺动脉高压的发生过程中发挥了重要作用。
Conclusion Serum VEGF contents increased at high altitude. It might play an important role in the developing process of hypoxia pulmonary hypertension.
目的：探讨雾化吸入硝酸甘油(ntg)对新生猪急性低氧性肺动脉高压和心肌损害的疗效和安全性。
AIM: To investigate the effects of nebulized nitroglycerin (NTG) on pulmonary, systemic hemodynamics and myocardial impairment during pulmonary hypertension induced by hypoxia in piglets.
结论：内质网应激介导的凋亡与大鼠慢性低氧性肺动脉高压、肺血管改建的病理过程有关。
Conclusion: the endoplasmic reticulum stress-induced apoptosis may be one of the mechanism of hypoxic pulmonary hypertension and pulmonary vascular wall remodeling.
目的：探讨肾上腺髓质素(AM)在慢性低氧性肺动脉高压发病中的作用。
AIM: To study the role of adrenomedullin (AM) in the pathogenesis of hypoxic pulmonary hypertension.
提示间断低氧过程中沛部氧自由基生成增多，可能参与了肺动脉高压的发病过程。
The results suggest that in the process of intermittent hypoxia in rats, generation of oxygen free radicals was increased in lung, which may play a role in pathogenesis of pulmonary hypertension.
目的：探讨外源性低浓度一氧化碳(CO)在低氧性肺动脉高压中的作用。
AIM: To explore the effect of exogenous carbon monoxide (CO) on the hypoxic pulmonary arterial hypertension in the rat.
目的：探讨外源性低浓度一氧化碳(CO)在低氧性肺动脉高压中的作用。
AIM: To explore the effect of exogenous carbon monoxide (CO) on the hypoxic pulmonary arterial hypertension in the rat.
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