目的探索线粒体ATP敏感钾通道在低氧预处理抗低氧性肺损伤中的作用。
Objective To observe the Role of Mitochondrial ATP Sensitive Potassium Channel in Hypoxic Preconditioning Against Hypoxic Pulmonary Injury.
背景：赛前的高原训练目的，是希望通过高原的低氧环境刺激，使运动员在训练中获得最大的低氧生理适应性。
BACKGROUND: High-altitude training before competition aims to obtain maximum hypoxia physiological adaptability of athletes through hypoxia environmental irritation at high altitude.
上述观察结果提示慢性间歇性低氧减弱急性缺氧对KV的抑制，这可能是机体低氧适应的一种重要机制。
The results suggest that KV inhibition was significantly attenuated by chronic intermittent hypoxia, and this effect may be a critical mechanism of the body hypoxic acclimatization.
低氧预适应可增强机体耐受低氧的能力，这种内源性保护现象存在于多种组织和器官。
Hypoxic preconditioning can improve the resistance against hypoxia which is an endogenous and protective phenomenon and exists in many tissues and organs.
结论低氧所致CTGF的合成增多在低氧性肺血管重建和肺动脉高压的发病过程中起一定的作用。
Conclusions: the CTGF may play an important role in the pathogenesis process of hypoxic pulmonary vascular remodeling and pulmonary hypertension.
结果表明，切除内脏大神经大鼠低氧时的红细胞参数改变与单纯低氧对照比较，无显著性差异。
The results suggested that the erythropoiesis in rats having bilateral splanchnic neurectomy was not significantly different from in intact rats when subjected to hypoxic hypoxia.
低氧诱导因子1 (HIF - 1)是重要的氧依赖性核转录因子，低氧条件下能上调多个靶基因表达以减少缺氧性损伤。
Hypoxia inducible factor-1 (HIF-1) is a key oxygen-dependent transcription factor that up-regulates many protective genes against hypoxia-induced injury.
对低氧造成膈肌疲劳的机制和机体对低氧后的适应性改变进行简要的介绍。
In this Review, we summarize the current knowledge regarding the effects of hypoxia on diaphragmatic fatigue, its mechanisms, and acclimatized alteration of diaphragm after hypoxic exposure.
中重度低氧血症患者各时点血糖水平较轻度低氧血症患者显著性增高（P<0 05） ；
The level of plasma glucose in the intermediate and severe hypoxemia groups before an after oral glucose load were higher than that in the moderate hypoxemia group(P<0.05).
结论高原低氧环境血清vegf的含量明显升高，可能在低氧性肺动脉高压的发生过程中发挥了重要作用。
Conclusion Serum VEGF contents increased at high altitude. It might play an important role in the developing process of hypoxia pulmonary hypertension.
方法：复制大鼠间断低氧4周模型，采用透射电镜和生化技术研究灯盏花注射液对慢性低氧性心肌损伤的治疗效果。
Methods: Transmission electron microscope and biochemical analysis were used to assay the therapeutic effect of Breviscapus Injection in rat model induced by 4 weeks hypoxia.
方法：复制大鼠间断低氧4周模型，采用透射电镜和生化技术研究灯盏花注射液对慢性低氧性心肌损伤的治疗效果。
Methods: Transmission electron microscope and biochemical analysis were used to assay the therapeutic effect of Breviscapus Injection in rat model induced by 4 weeks hypoxia.
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