但问题之一是:锁闭在这类受体之一之上的药物还可能附着在与之慎密亲密相关的受体之上,这可引起有害的副浸染。
But one of the problems is that a drug that latches on to one of these receptors might also attach to a closely related one, which can trigger unwanted side effects.
但当信号使受体激活并不被正确调控,CXCR4会促使癌的生长与扩散。
But when the signals that activate the receptor are not properly regulated, CXCR4 can spur the growth and spread of cancer.
虽然HIV外膜基因与毒株的细胞嗜性、受体使用,与介导融合等特性有关,但这些表型的体现与否,还与毒株的整个基因组背景有关。
Although env gene correlates with cell tropism, coreceptor usage and HIV syncytium inducing, it may have relationship with the whole genome, whether these phenotypes are present or not.
松弛素作用广泛,可与松弛素受体或糖皮质激素受体结合,但其受体后的确切机制以及不同生理和病理状态对松弛素的调控还需进一步基础研究阐明。
RLX exerts multiple effects, where the exact mechanisms behind the receptor-binding and modulation of RLX under different physiologic or pathologic conditions still need further elucidation.
松弛素作用广泛,可与松弛素受体或糖皮质激素受体结合,但其受体后的确切机制以及不同生理和病理状态对松弛素的调控还需进一步基础研究阐明。
RLX exerts multiple effects, where the exact mechanisms behind the receptor-binding and modulation of RLX under different physiologic or pathologic conditions still need further elucidation.
应用推荐