目的：探讨小儿甲型副伤寒的临床特征。
Objective:To investigate the clinical features of children paratyphoid fever.
甲型副伤寒早期临床症状以发热、头晕、头痛、咽干、咽痛、干咳为主，潜伏期7 ~ 27天，平均15天。
The first paratyphoid early clinical symptoms were mainly fever, dizzy, headache, pharyngoxerosis, pharynx-ache and dry-cough with 7-27 days of incubation period, average 15 days.
方法对我院1998—2004年收治的39例甲型副伤寒患者进行回顾性分析。
MethodsThe clinical data of 39 patients with paratyphoid fever a of our hospital from 1998 to 2004 were reviewed retrospectively.
目的探讨甲型副伤寒沙门菌的临床特点，以提高诊治水平。
Objective To investigate the clinical characteristic of Paratyphoid fever a infection, and enhance the diagnosis and treatment effects.
由体虱传播的流行性斑疹伤寒是最严重的一型，为人类史上的一大灾难，与拥挤、肮脏的人们形影相随。
Epidemic typhus spread by the body louse is the most severe. it is one of the great scourges of history associated with crowded filthy conditions.
近年来，我国南方一些地区以及东南亚某些国家均有甲型副伤寒沙门氏菌流行的报道。
Recently, there has some reports about Salmonella paratyphi a prevalence in our country and some other countries in southeast Asia.
方法：用12株鼠伤寒沙门菌分型噬菌体对3株体外诱导的鼠伤寒沙门菌l型及其原菌做噬菌体敏感性检测。
Methods: phage sensitivity of 3 strains of Salmonella typhimurium Lforms induced in vitro and their parents were tested by 12 strains of typing bacteriophages of Salmonella typhimurium.
目的：开展对伤寒病原学和耐药性监测以及伤寒噬菌体的分型研究，摸清伤寒流行规律，为制定防治措施提供依据。
Objective: In order to recognize the epidemic characteristics of Salmonella typhi and to provide scientific basis for formulating prevention and treatment measures.
本试验以甲型副伤寒沙门氏菌体抗原多克隆抗体的制备及提纯为例，提出可行的更简易的提纯方法。
In this experiment, we took the example of preparation and purification of polyclonal antibody of somatic antigen of Salmonella paratyphi a and found out a simpler feasible way of purification.
目的：探讨鼠伤寒沙门菌的L型变异对噬菌体敏感性的影响。
Objective: To investigated the effect on phage sensitivity resulting from the Lforms variation of Salmonella typhimurium.
伤寒以水型传播为主；
了解鼠伤寒沙门菌L型变异对细菌质粒和外膜蛋白的影响。
Aim:To investigate the influence of the L-forms variation of Salmonella typhimurium on their plasmids and outer membrane proteins.
我国每年均有不同程度的地方性甲型副伤寒流行及暴发，东南亚地区甲型副伤寒流行情况日趋严重。
The outbreaks caused by endemic S. paratyphi occur every year in some regions in China and the epidemic of typhoid is more serious in Southeast Asia.
结果贵州省9个市（州、地）26个县（区）的113株伤寒沙门菌和518株甲型副伤寒沙门菌对10种抗生素进行药物敏感性测定。
Results 113 S. typhi strains and 518 S. paratyphi strains in 26 counties and 9 cities were tested for drug sensitivity to 10 kinds of antibiotics.
同时从现场采集的样品中，检出4株丙型副伤寒沙门菌、3株婴儿沙门菌。
Meanwhile from the scene gathering sample, picks out 4 third paratyphoid salmonella bacilli, 3 baby salmonella bacilli.
本文综述了疫苗靶标蛋白的识别方法以及可能用于鉴别诊断或者疫苗有效靶标的潜在甲型副伤寒沙门菌抗原蛋白。
This paper summarizes the methods for identifying the vaccine targets and the list of potential s. paratyphi a antigens which could be used in differential diagnosis and as effective vaccine targets.
结论：2种方法同时应用可以互相补充，对于临床上早期确诊斑疹伤寒及准确分型，及时采取正确预防手段具有一定价值。
Conclusion: The combination of two methods has great value in clinical diagnosis and classification of murine typhus. It can decrease misdiagnosis rate and gives correct preventive suggestion.
随着甲型副伤寒沙门菌atcc 9150全基因组序列的公布，利用基因组和蛋白质组学的方法为研究甲型副伤寒沙门菌的疫苗靶标提供了良好的基础。
Along with the release of ATCC9150 whole genome sequence of S. paratyphi a, the methods using genome and proteomics would be useful for the study of vaccine targets aimed at S. paratyphi a.
通过以上研究工作，初步确定了甲型副伤寒沙门氏菌的夹心ELISA检测程序并优化了反应条件。
Through the study above, the detection procedure of sandwich indrect ELISA was decided, and the reacting conditions were optimized.
将甲型副伤寒沙门菌标准菌株按10- 1 ～ 10 -9稀释后扩增比较PCR的检测灵敏度。
The sensitivity of PCR assay was analyzed with 10 -1 ~10 -9 diluted.
将甲型副伤寒沙门菌标准菌株按10- 1 ～ 10 -9稀释后扩增比较PCR的检测灵敏度。
The sensitivity of PCR assay was analyzed with 10 -1 ~10 -9 diluted.
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