用伊文思蓝测定血脑屏障的通透性。
The Evans blue EB was used to test the permeability of blood brain barrier BBB.
方法以血脑屏障示踪剂伊文思蓝（E。
Methods With the tracer of blood-brain barrier Evans blue(E.
结果 伊文思蓝脂质体的包封率最高为 25 30 %。
Results The top encapsulation percentage of Evans blue liposome is 25 30%.
结果：脑创宁可明显减轻模型小鼠脑水肿程度，降低伊文思蓝含量，保护血脑屏障。
Result:Naochuangning could obviously lessen the level of cerebral edema and cut down the content of Evans blue and protect the blood brain barrier.
组织水平：通过检测脑组织中伊文思蓝（EB）的含量，定量分析安定对BBB通透性的影响。
Tissue level: Examining the content of the Evan's blue (EB) inside brain tissue was used to analysis the effect of diazepam on the BBB permeability quantitatively.
结果各时间点LPS组脑组织含水量、伊文思蓝（EB）含量、ICAM1表达情况及表达量均高于A组和NS组，差异有显著性（P< 0 .0 5 ）。
Results At each time point, the content of brain tissue, evans blue(EB) and the expressing quantity of ICAM 1 in LPS group increased significantly compared with group A and NS group(P<0.05).
结果各时间点LPS组脑组织含水量、伊文思蓝（EB）含量、ICAM1表达情况及表达量均高于A组和NS组，差异有显著性（P< 0 .0 5 ）。
Results At each time point, the content of brain tissue, evans blue(EB) and the expressing quantity of ICAM 1 in LPS group increased significantly compared with group A and NS group(P<0.05).
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