本文综述了药物基因组学的基本概念、高血压病和抗高血压药物反应异质性、与药物新陈代谢相关的基因、个体化治疗等方面的应用情况。
This review includes basic concepts of pharmacogenomics, heterogeneity of hypertension and antihypertensive drug responses, genes associate with drug metabolism, and individualized drug therapy.
本发明的药物组合物用于治疗和预防血容量不足，能够在大剂量输液进行扩容治疗时避免高氯代谢性酸中毒的风险。
The medicine composition is used for preventing and treating hypovolemia and may be used in great dosage infusion without risk of hyperchloremic metabolic acidosis.
因此，通过对各种糖代谢通路进行有针对性的干预，有望开发出新型治疗药物。
Hence it is hopeful to exploit new therapeutic drugs by pharmacological interference glycometabolism pathway.
目的探讨全身性热化疗治疗晚期胰腺癌的效果，以及化疗药物在此过程中代谢的变化。
Objective To investigate the effects of whole body hyperthermic chemotherapy for advanced pancreatic adenocarcinoma and the metabolic change of 5-fu during this experiment.
对于那些生成活性代谢物的药物来讲，经过首过代谢的治疗上的重要性取决于药物和代谢物所引起的期望的和非期望的效应。
For drugs with an active metabolite, the therapeutic consequence of first-pass metabolism depends on the contributions of the drug and the metabolite to the desired and undesired effects.
对于那些生成活性代谢物的药物来讲，经过首过代谢的治疗上的重要性取决于药物和代谢物所引起的期望的和非期望的效应。
For drugs with an active metabolite, the therapeutic consequence of first-pass metabolism depends on the contributions of the drug and the metabolite to the desired and undesired effects.
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