目的:探讨紫杉醇体外抑制人黑色素瘤细胞(A375细胞)增殖及诱导凋亡作用机制。
Objective: to investigate the growth-inhibitory and apoptosis-inducing effect of paclitaxel on human melanoma A375 cell and its mechanism in vitro.
PCL能抑制某些癌瘤细胞的生长,在测试的几种细胞中,对人黑色素瘤细胞m 21生长的抑制较为明显。
PCL had shown the inhibiting effect on growth of several tumor cells. Among the cells tested the effect on human melanoma M21 were shown to be the most strongly inhibited.
从罹患黑色素瘤的3人身上采得的肿瘤样本显示,纳米粒子找到了进入肿瘤细胞的方式。
Tumor samples taken from three people with melanoma showed the nanoparticles found their way inside tumor cells.
一组小鼠接种了人乳腺癌细胞,另一组则是黑色素瘤。
One set of mice was implanted with human breast cancer cells, the other with melanoma tumors.
注射人膀胱癌细胞、乳腺癌细胞、肺癌细胞或者黑色素瘤癌细胞的小鼠,给予PL可以抑制这些肿瘤的生长,但PL对正常小鼠未见毒性作用。
In mice injected with human bladder, breast, lung, or melanoma cancer cells, PL inhibited tumor growth but showed no toxicity in normal mice.
组织,细胞质蛋白,人肿瘤,黑色素瘤。
目的:探讨EGFR信号通路对人黑色素瘤A375细胞增殖、粘附和侵袭的影响及其分子机制。
Objective: To study the effect and mechanism of EGFR signaling pathway on proliferation, adhesion and invasion of A375 cells.
实事上,白癜风专家指出黑色素细胞的缺失(脱色)使人不再可能患黑色素瘤,而黑色素瘤是最严重的一种皮肤癌。
In fact, a vitiligo expert stated that with the total loss of melanocytes (depigmentation), it would be virtually impossible to get melanoma, the most serious form of skin cancer.
结论证实人恶性黑色素瘤a375细胞膜上表达MC 1r蛋白。MC1R基因的成功克隆为其进一步研究提供了必要条件。
Conclusion MC1R protein was successfully expressed on the membrane of human melanoma cell line A375. It provided a basis for the further study on MC1R.
测定壬二酸对人表皮黑素细胞和鼠黑色素瘤B16细胞酪氨酸酶活性及黑素含量变化观察壬二酸的脱色素作用。
The influence of azelaic acid on melanin synthesis and tyrosinase activity of human melanocytes and murine B16 melanoma cells were studied.
目的构建人G250真核表达载体,建立稳定表达人G250的小鼠黑色素瘤细胞系。
Objective To construct the human G250 eukaryotic expression vector and establish the stable B16 cell line expressing human G250 in mice.
目的构建人G250真核表达载体,建立稳定表达人G250的小鼠黑色素瘤细胞系。
Objective To construct the human G250 eukaryotic expression vector and establish the stable B16 cell line expressing human G250 in mice.
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