壬二酸抑制人表皮黑素细胞和鼠黑素瘤B16细胞的酪氨酸酶活性，细胞黑素合成减少，而且具有浓度依赖性。
The melanin synthesis and tyrosinase activity of human epidermal cells and murine B16 melanoma cells were inhibited by Azelaic acid in a dose-dependent manner.
测定壬二酸对人表皮黑素细胞和鼠黑色素瘤B16细胞酪氨酸酶活性及黑素含量变化观察壬二酸的脱色素作用。
The influence of azelaic acid on melanin synthesis and tyrosinase activity of human melanocytes and murine B16 melanoma cells were studied.
目的建立体外培养的正常人表皮黑素细胞系，检测壬二酸对人表皮黑素细胞和鼠黑素瘤B16细胞黑素合成的影响。
Objective To establish human normal melanocytes cell line in vitro and observe the effects of Azelaic acid on the pigment production of the epidermal melanocytes and B16 cells.
目的建立体外培养的正常人表皮黑素细胞系，检测壬二酸对人表皮黑素细胞和鼠黑素瘤B16细胞黑素合成的影响。
Objective To establish human normal melanocytes cell line in vitro and observe the effects of Azelaic acid on the pigment production of the epidermal melanocytes and B16 cells.
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