将4个鼠源噬菌体抗体克隆和1个人源噬菌体抗体克隆偶联到羧基终止的硅片表面,制成分析型模型芯片。
A model analytical chip was prepared by coupling 4 phage antibody clones from mouse and 1 clone from human to the surface of carboxyl terminated silicon.
采用正常人和白血病患者的白细胞对人源噬菌体抗体库进行淘选,以获得对两种细胞表面蛋白特异的抗体。
A large human phage antibody library was subjected for panning with leukocytes from healthy donors and leukemia patients to select for specific antibodies against leukocytic surface proteins.
目的:构建噬菌体人源抗独特型抗体库。
AIM: To construct phage human anti idiotypic antibody library.
目的构建人源抗红细胞A抗原单链噬菌体抗体库。
Objective To construct a phage display library of human single-chain Fv antibodies against blood group a substance.
为了构建人源性抗脑胶质瘤抗体库,我们必须先从患者的血液内检测到抗脑胶质瘤抗体,才能为建立人源性噬菌体抗体库奠定基础。
We must prove that there is really brain glioma antibody in the blood of patients, then we can establish the base for constructing humanized phage antibody library.
结论利用噬菌体抗体库技术获得了人源性抗角蛋白单链抗体,为临床应用研究提供了具有更广阔应用前景的人源小分子抗体。
Conclusion Human anti-keratin scFv is obtained from a large phage antibody library, which will benefit to the application of anti-keratin antibody to clinical research.
建立杂交瘤单抗亲和层析纯化抗原、抗原体外致敏淋巴细胞和RT-PCR克隆人抗体基因及噬菌体呈现技术构建人源抗体库的策略。
Strategy was established for construction of repertoire antibody library with affinity chromatography purifying antigen, antigen immunizing human lymphocytes, RT-PCR and phage display technology.
结论噬菌体抗体库技术是研制人源性单抗的有效途径。
Conclusion Phage surface display technology is a useful method to produce human monoclonal antibody against CEA.
结论噬菌体抗体库技术是研制人源性单抗的有效途径。
Conclusion Phage surface display technology is a useful method to produce human monoclonal antibody against CEA.
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