已发现耐亚胺培南菌株。
目的研究铜绿假单胞菌对亚胺培南耐药机制。
OBJECTIVE To study the mechanisms of imipenem resistance in Pseudomonas aeruginosa.
结果鲍氏不动杆菌对亚胺培南耐药率为41%；
RESULTS Among 62 A. baumannii strains, resistance to imipenem accounted for 41.0%;
亚胺培南最稳定。
亚胺培南是治疗肠杆菌科细菌感染的有效抗菌剂。
Imipenem was the most effective antibacterial agent for the treatment of Enterobacteriaceae infection.
亚胺培南、头孢他啶对不动杆菌的耐药率＜25％。
To Acinetobacter spp, the resistant rates of imipenem and Ceftazidime were less than 25%.
结论：建立的亚胺培南一水合物无菌检查法可供实用。
Conclusion: The established sterility test method for Imipenem monohydrate may be practical.
结果：左氧氟沙星对耐亚胺培南菌株的耐药率为43.48%；
Resuts: The resistant rate of 92 strains against imipenem resistant to levofloxacin was 43.48%.
定植菌以革兰阴性杆菌为主，亚胺培南对所用抗菌药物中最敏感。
Primary colonization bacteria were Gram-negative bacteria. Imipenem was the most sensitive antimicrobial drug in use at present.
结果：用亚胺培南-西司他丁钠盐的患者感染迅速被控制，疗效显著。
RESULTS: Infections in the patients given imipenem cilastatin sodium were rapidly controlled and the effects of which were definite.
结果：确定了亚胺培南一水合物无菌检查法的最佳冲洗条件及操作方法。
Results: the best washing condition and operation method for the sterility tests of Imipenem Monohydrate were determined.
目的研究亚胺培南在严重烧伤早期痂下组织液和血浆中的药代动力学变化。
Objective To study the change of pharmacokinetics parameters of imipenem in the interstitial fluids under eschar of burn rabbits in the early stage.
方法：回顾性分析亚胺培南治疗16例重症下呼吸道感染病例的疗效和不良反应。
Methods: a retrospective analysis was made concerning the therapeutic effects and adverse reactions of imipenem in the treatment 16 cases of severe infection of the LRT.
亚胺培南为儿童急性白血病化疗后粒细胞减少并发严重感染时十分有效的抗生素。
Imipenem was an effective antibiotics to children with septicemia in childhood leukemia with neutropenia.
前者对常用抗菌药物耐药率均>5 0 %，对亚胺培南的耐药率为81.82 %。
The drug resistance of PEA to common antibiotics was over 50 %, and to imipramine was 81.82%.
方法收集该院危重病房2005年1月至12月分离到的34株亚胺培南耐药鲍曼不动杆菌。
Methods Collected 34 strains of imipenem resistant Acinetobacter baumannii from 2005.1 to 2005.12 in ICU of our hospital.
金黄色葡萄球菌耐药性最严重，对甲氧西林的耐药性高达90%，但对亚胺培南敏感性达100%。
The most serious resistance are staphylococcus aureus, the resistance rate to 90%, but the sensitivity of 100% to the imipenem.
摘要：目的：分析国产与进口亚胺培南西司他丁钠治疗重症下呼吸道感染的成本-效果，并进行比较。
ABSTRACT: OBJECTIVE: to analyze and compare the cost-effectiveness of domestic and imported imipenem and cilastatin sodium for severe lower respiratory tract infection.
前言： 目的：选择对亚胺培南一水合物无菌检查的适宜检查方法，保证检验结果的准确性和可靠性。
Objective:The suitable method was selected for the sterility tests of Imipenem Monohydrate to guarantee the test result accurate and reliable.
肠杆菌科细菌对美罗培南和亚胺培南的敏感率最高（100%），而对环丙沙星的敏感率仅为12%左右；
The susceptibility rate of meropenem and imipenem to ciprofloxacin was 100%, while that of Escherichia coli and Klebsiella spp to ciprofloxacin was only 12%.
药敏分析发现G菌对亚胺培南最为敏感，而对青霉素、庆大霉素、头孢氨苄、克林霉素等的耐药率均超过50%。
According to the drug sensitive test, Gbacillus was most sensitive to imipenem but its drug resistance to penicillin, cidomycin, cefalexin, clindamycin ect was more than 50%.
药敏试验表明：铜绿假单胞菌对亚胺培南（IMP）的敏感率为62.0%，对其他所有抗菌药物的敏感率均低于60%。
The sensitive rate of P. aeruginosa to imipenem (IMP) was 62.0%, but was lower than 60.0% to other antimicrobial agents.
方法对医院临床分离的8株耐亚胺培南铜绿假单胞菌进行随机引物聚合酶链反应（PCR）扩增，扩增产物进行电泳和聚类分析。
METHODS The genes of imipenem-resistant P. aeruginosa were amplified by RAPD assay in 8 clinical isolates and PCR products were analyzed by agarose gel electrophoresis and cluster analysis.
方法对医院临床分离的8株耐亚胺培南铜绿假单胞菌进行随机引物聚合酶链反应（PCR）扩增，扩增产物进行电泳和聚类分析。
METHODS The genes of imipenem-resistant P. aeruginosa were amplified by RAPD assay in 8 clinical isolates and PCR products were analyzed by agarose gel electrophoresis and cluster analysis.
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