目的研究铜绿假单胞菌对亚胺培南耐药机制。
OBJECTIVE To study the mechanisms of imipenem resistance in Pseudomonas aeruginosa.
结果鲍氏不动杆菌对亚胺培南耐药率为41%；
RESULTS Among 62 A. baumannii strains, resistance to imipenem accounted for 41.0%;
方法收集该院危重病房2005年1月至12月分离到的34株亚胺培南耐药鲍曼不动杆菌。
Methods Collected 34 strains of imipenem resistant Acinetobacter baumannii from 2005.1 to 2005.12 in ICU of our hospital.
金黄色葡萄球菌耐药性最严重，对甲氧西林的耐药性高达90%，但对亚胺培南敏感性达100%。
The most serious resistance are staphylococcus aureus, the resistance rate to 90%, but the sensitivity of 100% to the imipenem.
亚胺培南、头孢他啶对不动杆菌的耐药率＜25％。
To Acinetobacter spp, the resistant rates of imipenem and Ceftazidime were less than 25%.
药敏分析发现G菌对亚胺培南最为敏感，而对青霉素、庆大霉素、头孢氨苄、克林霉素等的耐药率均超过50%。
According to the drug sensitive test, Gbacillus was most sensitive to imipenem but its drug resistance to penicillin, cidomycin, cefalexin, clindamycin ect was more than 50%.
前者对常用抗菌药物耐药率均>5 0 %，对亚胺培南的耐药率为81.82 %。
The drug resistance of PEA to common antibiotics was over 50 %, and to imipramine was 81.82%.
结果：左氧氟沙星对耐亚胺培南菌株的耐药率为43.48%；
Resuts: The resistant rate of 92 strains against imipenem resistant to levofloxacin was 43.48%.
结果：左氧氟沙星对耐亚胺培南菌株的耐药率为43.48%；
Resuts: The resistant rate of 92 strains against imipenem resistant to levofloxacin was 43.48%.
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