亚硝基脲的抗癌与致癌机理是非常接近的,都能够使DNA碱基发生烷化,进一步形成DNA股间交联。
The anticancer mechanism of nitrosoureas is very similar to the carcinogenic mechanism, both of them can alkylate DNA bases and form DNA cross-linking further.
接种细胞一天后,用不同剂量乙基亚硝基脲(ENU)处理2小时,然后用标准法检查其染色体畸变和SCE率,用细胞计数法测定细胞毒性。
One day after plating, the cells were exposed for 2 h to various doses of ethylnitrosourea (ENU). CAs and SCEs were examined by the standard methods, while CT was determined by cell counts.
目的探讨亚硝基乙基脲(NEU)经胎盘诱发脑肿瘤动物模型的时间和剂量依赖性。
Objective To study time and dose dependence of animal models with brain neoplasms induced transplacentally with N-ethyl-N-nitrosourea (NEU).
目的探讨亚硝基乙基脲(NEU)经胎盘诱发脑肿瘤动物模型的时间和剂量依赖性。
Objective To study time and dose dependence of animal models with brain neoplasms induced transplacentally with N-ethyl-N-nitrosourea (NEU).
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