笔者讨论了一些五环三萜类化合物的药理活性与结构的关系。
This article is reviewing the structure-activity relationship of pentacyclic triterpenes.
目的：对天然五环三萜进行结构修饰，寻找新型糖原代谢调控药物。
Aim: to search for novel modulators of glycogen metabolism through structural modifications of natural pentacyclic triterpenes.
典型的标志如卟啉、姥鲛烷、植烷、留烷、胡萝卜烷、以及五环三萜烷。
Typical markers are the porphyrins, pristine, phytane, steranes, carotenes and pentacyclic triterpanes.
熊果酸属于五环三萜类化合物，广泛存在于天然植物中，具有多种显著的药理活性。
Ursolic acid, a pentacyclic triterpene compound, naturally occurs in a large variety of plants, has attracted considerable interest owing to its significant biological activities.
五环三萜是一类重要的天然产物，研究发现生物转化能够对该类化合物进行多种类型的结构修饰。
Pentacyclic triterpenes are among the most important bioactive compounds and biotransformation is a very useful tool to carry out the structural modification on these compounds.
其主要功能成分是人参皂苷，即达玛烷型四环三萜类或香树脂烷型五环三萜类化合物，至今人参皂苷尚未能人工合成。
Ginsenoside, the main components of ginseng, is dammarane tetracyclic triterpenoids or hong resin alkyl type pentacyclic triterpene, which has not yet been synthesized artificially.
其主要功能成分是人参皂苷，即达玛烷型四环三萜类或香树脂烷型五环三萜类化合物，至今人参皂苷尚未能人工合成。
Ginsenoside, the main components of ginseng, is dammarane tetracyclic triterpenoids or hong resin alkyl type pentacyclic triterpene, which has not yet been synthesized artificially.
应用推荐